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lectin-21Ca [ Drosophila melanogaster (fruit fly) ]

Gene ID: 53552, updated on 10-May-2024

Summary

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Official Symbol
lectin-21Caprovided by FlyBase
Primary source
FLYBASE:FBgn0040107
Locus tag
Dmel_CG2826
See related
AllianceGenome:FB:FBgn0040107
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AC 004573A; AC004573a; CG2826; Dmel\CG2826; Lectin-21Ca
Summary
Predicted to enable galactose binding activity. Involved in multicellular organism reproduction. Predicted to be located in extracellular region. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in 3MC syndrome 2. Orthologous to human COLEC11 (collectin subfamily member 11). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See lectin-21Ca in Genome Data Viewer
Location:
21E2-21E2; 2-1.5 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (624617..625556)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (624617..625556)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44797 Neighboring gene long non-coding RNA:CR44798 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45369

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Neighbourhood continuity is not required for correct testis gene expression in Drosophila. Meadows LA, et al. PLoS Biol, 2010 Nov 30. PMID 21151342, Free PMC Article
  2. Molecular evolution and population genetics of duplicated accessory gland protein genes in Drosophila. Holloway AK, et al. Mol Biol Evol, 2004 Sep. PMID 15215320
  3. Lectin-like proteins in model organisms: implications for evolution of carbohydrate-binding activity. Dodd RB, et al. Glycobiology, 2001 May. PMID 11425795
  4. Insect glycobiology: a lectin multigene family in Drosophila melanogaster. Theopold U, et al. Biochem Biophys Res Commun, 1999 Aug 11. PMID 10441526
  5. Comparative genomic analysis of C-type lectin-domain genes in seven holometabolous insect species. Lu Y, et al. Insect Biochem Mol Biol, 2020 Nov. PMID 32841718

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbohydrate binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables galactose binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological process involved in interspecies interaction between organisms IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sexual reproduction IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
lectin-21Ca
Names
CG2826-PA
Lectin21Ca
lectin-21Ca-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    624617..625556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_144385.3 → NP_652642.2  lectin-21Ca [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652642.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3DNH5, Q9VPS2
    Conserved Domains (1) summary
    cd00037
    Location:158 → 265
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VPS2 Q9VPS2

Gene LinkOut

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