Format

Send to:

Choose Destination

PFN2 profilin 2 [ Bos taurus (cattle) ]

Gene ID: 539034, updated on 12-Oct-2019

Summary

Official Symbol
PFN2provided by VGNC
Official Full Name
profilin 2provided by VGNC
Primary source
VGNC:VGNC:32776
See related
Ensembl:ENSBTAG00000011150
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs

Genomic context

See PFN2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 1 NC_037328.1 (118211474..118220079)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 1 AC_000158.1 (119151057..119157811)

Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104971004 Neighboring gene uncharacterized LOC101905340 Neighboring gene ring finger protein 13 Neighboring gene ankyrin repeat and ubiquitin domain containing 1

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATPase activity IEA
Inferred from Electronic Annotation
more info
 
actin monomer binding IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol-4,5-bisphosphate binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
modification of postsynaptic actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
negative regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
 
negative regulation of epithelial cell migration IEA
Inferred from Electronic Annotation
more info
 
negative regulation of ruffle assembly IEA
Inferred from Electronic Annotation
more info
 
positive regulation of ATPase activity IEA
Inferred from Electronic Annotation
more info
 
positive regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
 
positive regulation of peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of stress fiber assembly IEA
Inferred from Electronic Annotation
more info
 
protein stabilization IEA
Inferred from Electronic Annotation
more info
 
regulation of synaptic vesicle exocytosis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Schaffer collateral - CA1 synapse IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
postsynapse IEA
Inferred from Electronic Annotation
more info
 
presynapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
profilin-2
Names
profilin II

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128197.1NP_001121669.1  profilin-2

    See identical proteins and their annotated locations for NP_001121669.1

    Status: PROVISIONAL

    Source sequence(s)
    BC122616
    UniProtKB/Swiss-Prot
    Q09430
    Related
    ENSBTAP00000014805.5, ENSBTAT00000014805.6
    Conserved Domains (1) summary
    smart00392
    Location:2140
    PROF; Profilin

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037328.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    118211474..118220079
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005201812.4XP_005201869.1  profilin-2 isoform X1

    See identical proteins and their annotated locations for XP_005201869.1

    Conserved Domains (1) summary
    smart00392
    Location:2139
    PROF; Profilin
Support Center