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TRAF1 TNF receptor associated factor 1 [ Bos taurus (cattle) ]

Gene ID: 540944, updated on 5-Mar-2024

Summary

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Official Symbol
TRAF1provided by VGNC
Official Full Name
TNF receptor associated factor 1provided by VGNC
Primary source
VGNC:VGNC:36270
See related
BGD:BT12285; Ensembl:ENSBTAG00000003012
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See TRAF1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (110293213..110317278, complement)

Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene cutA divalent cation tolerance like Neighboring gene PHD finger protein 19 Neighboring gene complement C5 Neighboring gene complement C5-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 1
NP_001179730.1
XP_005210651.1
XP_005210652.1
XP_005210654.1
XP_005210655.1
XP_010806622.1
XP_015328211.1
XP_059745197.1
XP_059745198.1
XP_059745199.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192801.1 → NP_001179730.1  TNF receptor-associated factor 1

    See identical proteins and their annotated locations for NP_001179730.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000008
    UniProtKB/TrEMBL
    E1BMI8
    Conserved Domains (2) summary
    cd03779
    Location:266 → 412
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam16673
    Location:183 → 243
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    110293213..110317278 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010808320.4 → XP_010806622.1  TNF receptor-associated factor 1 isoform X2

    See identical proteins and their annotated locations for XP_010806622.1

    UniProtKB/TrEMBL
    E1BMI8
    Conserved Domains (2) summary
    cd03779
    Location:266 → 412
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam16673
    Location:183 → 243
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  2. XM_005210597.5 → XP_005210654.1  TNF receptor-associated factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A3Q1LN53
    Related
    ENSBTAP00000061380.1, ENSBTAT00000067280.2
    Conserved Domains (2) summary
    cd03779
    Location:231 → 377
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam16673
    Location:148 → 208
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  3. XM_005210598.5 → XP_005210655.1  TNF receptor-associated factor 1 isoform X1

    Conserved Domains (2) summary
    cd03779
    Location:164 → 310
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam16673
    Location:81 → 141
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  4. XM_005210594.5 → XP_005210651.1  TNF receptor-associated factor 1 isoform X2

    See identical proteins and their annotated locations for XP_005210651.1

    UniProtKB/TrEMBL
    E1BMI8
    Conserved Domains (2) summary
    cd03779
    Location:266 → 412
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam16673
    Location:183 → 243
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  5. XM_059889215.1 → XP_059745198.1  TNF receptor-associated factor 1 isoform X2

    UniProtKB/TrEMBL
    E1BMI8

  6. XM_059889214.1 → XP_059745197.1  TNF receptor-associated factor 1 isoform X2

    UniProtKB/TrEMBL
    E1BMI8

  7. XM_015472725.3 → XP_015328211.1  TNF receptor-associated factor 1 isoform X4

    Related
    ENSBTAP00000041215.4, ENSBTAT00000043659.5
    Conserved Domains (2) summary
    cd03779
    Location:251 → 397
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam16673
    Location:168 → 228
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  8. XM_005210595.5 → XP_005210652.1  TNF receptor-associated factor 1 isoform X2

    See identical proteins and their annotated locations for XP_005210652.1

    UniProtKB/TrEMBL
    E1BMI8
    Conserved Domains (2) summary
    cd03779
    Location:266 → 412
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam16673
    Location:183 → 243
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  9. XM_059889216.1 → XP_059745199.1  TNF receptor-associated factor 1 isoform X3

    Related
    ENSBTAP00000097499.1, ENSBTAT00000120190.1
Nucleotide Protein Strain
Heading Accession and Version

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