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Rdh7 retinol dehydrogenase 7 [ Mus musculus (house mouse) ]

Gene ID: 54150, updated on 23-Jun-2021

Summary

Official Symbol
Rdh7provided by MGI
Official Full Name
retinol dehydrogenase 7provided by MGI
Primary source
MGI:MGI:1860517
See related
Ensembl:ENSMUSG00000040134
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CRA; CRAD2; AI194929
Expression
Biased expression in liver adult (RPKM 592.0) and liver E18 (RPKM 146.7) See more
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Genomic context

See Rdh7 in Genome Data Viewer
Location:
10; 10 D3
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (127719896..127725116, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (127884027..127889247, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (127321083..127326303, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene retinol dehydrogenase 19 Neighboring gene RDH16 family member 2 Neighboring gene predicted gene, 31091 Neighboring gene 4short chain dehydrogenase/reductase family 9C, member 7 Neighboring gene predicted gene, 40804

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables NAD-retinol dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
enables androstan-3-alpha,17-beta-diol dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
enables androsterone dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
enables catalytic activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in steroid metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
retinol dehydrogenase 7
Names
CRAD-2
cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme 2
cis-retinol/androgen dehydrogenase type 2
NP_001144221.1
NP_059501.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001150749.1NP_001144221.1  retinol dehydrogenase 7 precursor

    See identical proteins and their annotated locations for NP_001144221.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AB015165, AI255893, CB951082, CJ097101
    Consensus CDS
    CCDS24255.1
    UniProtKB/Swiss-Prot
    O88451
    Related
    ENSMUSP00000039252.5, ENSMUST00000047199.5
    Conserved Domains (2) summary
    cd09805
    Location:30305
    type2_17beta_HSD-like_SDR_c; human 17beta-hydroxysteroid dehydrogenase type 2 (type 2 17beta-HSD)-like, classical (c) SDRs
    pfam00106
    Location:30217
    adh_short; short chain dehydrogenase
  2. NM_017473.4NP_059501.1  retinol dehydrogenase 7 precursor

    See identical proteins and their annotated locations for NP_059501.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different segment for its 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AA260496, AC131690, AF056194
    Consensus CDS
    CCDS24255.1
    UniProtKB/Swiss-Prot
    O88451
    Conserved Domains (2) summary
    cd09805
    Location:30305
    type2_17beta_HSD-like_SDR_c; human 17beta-hydroxysteroid dehydrogenase type 2 (type 2 17beta-HSD)-like, classical (c) SDRs
    pfam00106
    Location:30217
    adh_short; short chain dehydrogenase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    127719896..127725116 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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