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Zfp316 zinc finger protein 316 [ Mus musculus (house mouse) ]

Gene ID: 54201, updated on 11-Apr-2024

Summary

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Official Symbol
Zfp316provided by MGI
Official Full Name
zinc finger protein 316provided by MGI
Primary source
MGI:MGI:1860402
See related
Ensembl:ENSMUSG00000046658 AllianceGenome:MGI:1860402
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mzf3; Emzf1; Znf316
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system. Orthologous to human ZNF316 (zinc finger protein 316). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 8.9), adrenal adult (RPKM 7.2) and 24 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 G2; 5 82.03 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (143235450..143258269, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (143249695..143270031, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930448H16 gene Neighboring gene predicted gene, 38735 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:143996641-143996853 Neighboring gene zinc finger protein 12 Neighboring gene cDNA sequence BC030343 Neighboring gene zinc finger protein 853 Neighboring gene predicted gene, 52794

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population. Mugford JW, et al. Dev Biol, 2009 Sep 15. PMID 19591821, Free PMC Article
  2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  3. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 316
Names
kruppel-related zinc finger protein
transcription factor MZF-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017467.3 → NP_059495.3  zinc finger protein 316

    See identical proteins and their annotated locations for NP_059495.3

    Status: VALIDATED

    Source sequence(s)
    AC123686, BC057078
    Consensus CDS
    CCDS19838.2
    UniProtKB/Swiss-Prot
    Q6PGE4
    UniProtKB/TrEMBL
    G3XA34
    Related
    ENSMUSP00000125416.2, ENSMUST00000161448.8
    Conserved Domains (6) summary
    smart00349
    Location:155 → 215
    KRAB; krueppel associated box
    COG5048
    Location:763 → 950
    COG5048; FOG: Zn-finger [General function prediction only]
    PRK13108
    Location:507 → 584
    PRK13108; prolipoprotein diacylglyceryl transferase; Reviewed
    sd00017
    Location:850 → 870
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:710 → 730
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:383 → 408
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    143235450..143258269 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006504718.5 → XP_006504781.1  zinc finger protein 316 isoform X1

    See identical proteins and their annotated locations for XP_006504781.1

    UniProtKB/Swiss-Prot
    Q6PGE4
    UniProtKB/TrEMBL
    G3XA34
    Conserved Domains (6) summary
    smart00349
    Location:155 → 215
    KRAB; krueppel associated box
    COG5048
    Location:763 → 950
    COG5048; FOG: Zn-finger [General function prediction only]
    PRK13108
    Location:507 → 584
    PRK13108; prolipoprotein diacylglyceryl transferase; Reviewed
    sd00017
    Location:850 → 870
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:710 → 730
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:383 → 408
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PGE4.1 GenPept UniProtKB/Swiss-Prot:Q6PGE4

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