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Or10ad1c olfactory receptor family 10 subfamily AD member 1C [ Mus musculus (house mouse) ]

Gene ID: 545140, updated on 11-Apr-2024

Summary

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Official Symbol
Or10ad1cprovided by MGI
Official Full Name
olfactory receptor family 10 subfamily AD member 1Cprovided by MGI
Primary source
MGI:MGI:3030122
See related
Ensembl:ENSMUSG00000075427 AllianceGenome:MGI:3030122
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr288; MOR286-3P; GA_x5J8B7W76D0-7609197-7608973
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Biased expression in cortex adult (RPKM 1.1), frontal lobe adult (RPKM 1.1) and 7 other tissues See more
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Genomic context

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See Or10ad1c in Genome Data Viewer
Location:
15 F1; 15 54.19 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (98083892..98093423, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (98186011..98195542, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39652 Neighboring gene ankyrin repeat and SOCS box-containing 8 Neighboring gene STARR-seq mESC enhancer starr_39654 Neighboring gene STARR-positive B cell enhancer ABC_E5515 Neighboring gene coiled-coil domain containing 184 Neighboring gene predicted gene, 33909 Neighboring gene olfactory receptor family 10 subfamily AD member 1 Neighboring gene olfactory receptor family 10 subfamily AD member 1B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Contribution of individual olfactory receptors to odor-induced attractive or aversive behavior in mice. Horio N, et al. Nat Commun, 2019 Jan 14. PMID 30643144, Free PMC Article
  2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within detection of chemical stimulus involved in sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 

General protein information

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Preferred Names
olfactory receptor 288
Names
olfactory receptor MOR286-3P

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011733.2 → NP_001011733.2  olfactory receptor 288

    Status: VALIDATED

    Source sequence(s)
    AC105982, BG080619, C85333
    Consensus CDS
    CCDS49719.1
    UniProtKB/TrEMBL
    E9Q1P2, Q7TS14
    Related
    ENSMUSP00000132237.2, ENSMUST00000165379.8
    Conserved Domains (2) summary
    cd14964
    Location:67 → 89
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:42 → 301
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    98083892..98093423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017316704.3 → XP_017172193.2  olfactory receptor 288 isoform X1

    UniProtKB/TrEMBL
    E9Q1P2, Q7TS14
    Conserved Domains (2) summary
    cd14964
    Location:67 → 89
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:42 → 301
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein Strain
Heading Accession and Version

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