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Extl3 exostosin-like glycosyltransferase 3 [ Mus musculus (house mouse) ]

Gene ID: 54616, updated on 16-Aug-2021

Summary

Official Symbol
Extl3provided by MGI
Official Full Name
exostosin-like glycosyltransferase 3provided by MGI
Primary source
MGI:MGI:1860765
See related
Ensembl:ENSMUSG00000021978
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ext1l; AU040105; mKIAA0519; 2900009G18Rik
Expression
Ubiquitous expression in subcutaneous fat pad adult (RPKM 31.2), mammary gland adult (RPKM 19.2) and 27 other tissues See more
Orthologs
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Genomic context

See Extl3 in Genome Data Viewer
Location:
14; 14 D1
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (65289508..65387349, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65052059..65149899, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (65670896..65716943, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene homeobox containing 1 Neighboring gene high mobility group nucleosomal binding domain 2, pseudogene Neighboring gene integrator complex subunit 9 Neighboring gene predicted gene, 52118 Neighboring gene predicted gene, 52119 Neighboring gene predicted gene, 30008 Neighboring gene predicted gene, 41177 Neighboring gene frizzled class receptor 3 Neighboring gene predicted gene 9086

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0519

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables glycosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in heparan sulfate proteoglycan biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell growth ISO
Inferred from Sequence Orthology
more info
 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
exostosin-like 3
Names
exostoses (multiple)-like 3
exostoses-like 3
exostosin
glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
multiple exostosis-like protein 3
NP_001347314.1
NP_061258.2
XP_006519347.1
XP_006519349.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360385.1NP_001347314.1  exostosin-like 3

    Status: VALIDATED

    Source sequence(s)
    AC155172, BC065073, CJ129577, CO044892
    Consensus CDS
    CCDS27211.1
    Conserved Domains (3) summary
    pfam03016
    Location:190500
    Exostosin; Exostosin family
    pfam07926
    Location:76150
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam09258
    Location:663900
    Glyco_transf_64; Glycosyl transferase family 64 domain
  2. NM_018788.3NP_061258.2  exostosin-like 3

    See identical proteins and their annotated locations for NP_061258.2

    Status: VALIDATED

    Source sequence(s)
    AC155172, BC065073, CJ129577, CO044892
    Consensus CDS
    CCDS27211.1
    UniProtKB/TrEMBL
    Q6P1H4
    Related
    ENSMUSP00000022550.8, ENSMUST00000022550.8
    Conserved Domains (3) summary
    pfam03016
    Location:190500
    Exostosin; Exostosin family
    pfam07926
    Location:76150
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam09258
    Location:663900
    Glyco_transf_64; Glycosyl transferase family 64 domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    65289508..65387349 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519284.3XP_006519347.1  exostosin-like 3 isoform X1

    See identical proteins and their annotated locations for XP_006519347.1

    UniProtKB/TrEMBL
    Q6P1H4
    Conserved Domains (3) summary
    pfam03016
    Location:190500
    Exostosin; Exostosin family
    pfam07926
    Location:76150
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam09258
    Location:663900
    Glyco_transf_64; Glycosyl transferase family 64 domain
  2. XM_006519286.4XP_006519349.1  exostosin-like 3 isoform X1

    See identical proteins and their annotated locations for XP_006519349.1

    UniProtKB/TrEMBL
    Q6P1H4
    Conserved Domains (3) summary
    pfam03016
    Location:190500
    Exostosin; Exostosin family
    pfam07926
    Location:76150
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam09258
    Location:663900
    Glyco_transf_64; Glycosyl transferase family 64 domain
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