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SYTL2 synaptotagmin like 2 [ Homo sapiens (human) ]

Gene ID: 54843, updated on 23-Nov-2021

Summary

Official Symbol
SYTL2provided by HGNC
Official Full Name
synaptotagmin like 2provided by HGNC
Primary source
HGNC:HGNC:15585
See related
Ensembl:ENSG00000137501 MIM:612880
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EXO4; SLP2; SLP2A; SGA72M; CHR11SYT; PPP1R151
Summary
The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jun 2009]
Expression
Broad expression in stomach (RPKM 22.4), colon (RPKM 16.3) and 17 other tissues See more
Orthologs
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Genomic context

See SYTL2 in Genome Data Viewer
Location:
11q14.1
Exon count:
25
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (85694229..85854870, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (85405264..85522184, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene CREB/ATF bZIP transcription factor Neighboring gene coiled-coil domain containing 89 Neighboring gene coiled-coil domain containing 83 Neighboring gene adenosylhomocysteinase pseudogene 6 Neighboring gene solute carrier family 25 member 1 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Silencing of SLP2 by shRNA inhibits HIV-1 replication in Jurkat cells PubMed

Protein interactions

Protein Gene Interaction Pubs
Pr55(Gag) gag SLP2 is a Rab27a effector required for HIV-1 Gag assembly at the plasma membrane in Jurkat cells PubMed
gag Silencing the expression of SLP2 leads to a diffuse intracellular HIV-1 Gag staining pattern accompanied by a dramatic reduction in the association of Gag with the plasma membrane PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21219, FLJ34802, FLJ42764, FLJ45597, KIAA1597, MGC102768

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables neurexin family protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables neurexin family protein binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables phosphatase binding IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphatidylinositol-4,5-bisphosphate binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables phosphatidylserine binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in exocytosis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle docking involved in exocytosis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in exocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in exocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in extrinsic component of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in melanosome ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
synaptotagmin-like protein 2
Names
breast cancer-associated antigen SGA-72M
chromosome 11 synaptotagmin
exophilin-4
protein phosphatase 1, regulatory subunit 151

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029712.2 RefSeqGene

    Range
    4977..121915
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001162951.4NP_001156423.1  synaptotagmin-like protein 2 isoform g

    See identical proteins and their annotated locations for NP_001156423.1

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Consensus CDS
    CCDS53688.1
    UniProtKB/Swiss-Prot
    Q9HCH5
    Related
    ENSP00000431701.1, ENST00000528231.5
    Conserved Domains (3) summary
    cd04020
    Location:769925
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:629756
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  2. NM_001162952.3NP_001156424.1  synaptotagmin-like protein 2 isoform h

    See identical proteins and their annotated locations for NP_001156424.1

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Consensus CDS
    CCDS53687.1
    UniProtKB/Swiss-Prot
    Q9HCH5
    Conserved Domains (2) summary
    cd04020
    Location:171327
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:31158
    C2; C2 domain
  3. NM_001162953.4NP_001156425.1  synaptotagmin-like protein 2 isoform i

    See identical proteins and their annotated locations for NP_001156425.1

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Consensus CDS
    CCDS53689.1
    UniProtKB/Swiss-Prot
    Q9HCH5
    Related
    ENSP00000352065.6, ENST00000359152.9
    Conserved Domains (3) summary
    cd04020
    Location:770926
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:630757
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  4. NM_001289608.2NP_001276537.1  synaptotagmin-like protein 2 isoform j

    See identical proteins and their annotated locations for NP_001276537.1

    Status: REVIEWED

    Source sequence(s)
    AK124754, AK296224, EU035829
    Consensus CDS
    CCDS76461.1
    UniProtKB/Swiss-Prot
    Q9HCH5
    Related
    ENSP00000434010.1, ENST00000527523.5
    Conserved Domains (2) summary
    cd04020
    Location:737893
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:597724
    C2; C2 domain
  5. NM_001289609.2NP_001276538.1  synaptotagmin-like protein 2 isoform k

    Status: REVIEWED

    Source sequence(s)
    AP000642
    UniProtKB/Swiss-Prot
    Q9HCH5
    Conserved Domains (2) summary
    cd04020
    Location:90246
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:1477
    C2; C2 domain
  6. NM_001289610.2NP_001276539.1  synaptotagmin-like protein 2 isoform h

    See identical proteins and their annotated locations for NP_001276539.1

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Consensus CDS
    CCDS53687.1
    UniProtKB/Swiss-Prot
    Q9HCH5
    Related
    ENSP00000432144.1, ENST00000533892.5
    Conserved Domains (2) summary
    cd04020
    Location:171327
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:31158
    C2; C2 domain
  7. NM_001365826.2NP_001352755.1  synaptotagmin-like protein 2 isoform l

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:746902
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:606733
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  8. NM_001365827.2NP_001352756.1  synaptotagmin-like protein 2 isoform m

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:697853
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:557684
    C2; C2 domain
  9. NM_001365828.2NP_001352757.1  synaptotagmin-like protein 2 isoform b

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Related
    ENSP00000432996.1, ENST00000525702.5
    Conserved Domains (2) summary
    cd04020
    Location:211367
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:71198
    C2; C2 domain
  10. NM_001365829.2NP_001352758.1  synaptotagmin-like protein 2 isoform b

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Conserved Domains (2) summary
    cd04020
    Location:211367
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:71198
    C2; C2 domain
  11. NM_001365830.2NP_001352759.1  synaptotagmin-like protein 2 isoform b

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Conserved Domains (2) summary
    cd04020
    Location:211367
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:71198
    C2; C2 domain
  12. NM_001365831.2NP_001352760.1  synaptotagmin-like protein 2 isoform n

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Conserved Domains (2) summary
    cd04020
    Location:160316
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:20147
    C2; C2 domain
  13. NM_001365832.2NP_001352761.1  synaptotagmin-like protein 2 isoform o

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Conserved Domains (2) summary
    cd04020
    Location:103259
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:2092
    C2; C2 domain
  14. NM_001365833.2NP_001352762.1  synaptotagmin-like protein 2 isoform f

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Conserved Domains (2) summary
    cd04020
    Location:200356
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:60187
    C2; C2 domain
  15. NM_001365834.2NP_001352763.1  synaptotagmin-like protein 2 isoform p

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Conserved Domains (2) summary
    cd04020
    Location:143299
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:60132
    C2; C2 domain
  16. NM_001365835.2NP_001352764.1  synaptotagmin-like protein 2 isoform q

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Conserved Domains (2) summary
    cd04020
    Location:264420
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:124251
    C2; C2 domain
  17. NM_001394447.1NP_001381376.1  synaptotagmin-like protein 2 isoform r

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:20732229
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:19332060
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  18. NM_001394448.1NP_001381377.1  synaptotagmin-like protein 2 isoform s

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:20582214
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:19182045
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  19. NM_001394449.1NP_001381378.1  synaptotagmin-like protein 2 isoform s

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:20582214
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:19182045
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  20. NM_001394450.1NP_001381379.1  synaptotagmin-like protein 2 isoform t

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:20312187
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:18912018
    C2; C2 domain
  21. NM_001394451.1NP_001381380.1  synaptotagmin-like protein 2 isoform u

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:20302186
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:18902017
    C2; C2 domain
  22. NM_001394452.1NP_001381381.1  synaptotagmin-like protein 2 isoform v

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (1) summary
    cd04020
    Location:18702026
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
  23. NM_001394453.1NP_001381382.1  synaptotagmin-like protein 2 isoform w

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:786942
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:646773
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  24. NM_001394454.1NP_001381383.1  synaptotagmin-like protein 2 isoform w

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:786942
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:646773
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  25. NM_001394455.1NP_001381384.1  synaptotagmin-like protein 2 isoform x

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:785941
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:645772
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  26. NM_001394456.1NP_001381385.1  synaptotagmin-like protein 2 isoform x

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:785941
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:645772
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  27. NM_001394457.1NP_001381386.1  synaptotagmin-like protein 2 isoform g

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:769925
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:629756
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  28. NM_001394458.1NP_001381387.1  synaptotagmin-like protein 2 isoform g

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:769925
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:629756
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  29. NM_001394459.1NP_001381388.1  synaptotagmin-like protein 2 isoform g

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:769925
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:629756
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  30. NM_001394460.1NP_001381389.1  synaptotagmin-like protein 2 isoform y

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:759915
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:619746
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  31. NM_001394461.1NP_001381390.1  synaptotagmin-like protein 2 isoform z

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:758914
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:618745
    C2; C2 domain
  32. NM_001394462.1NP_001381391.1  synaptotagmin-like protein 2 isoform aa

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:743899
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:603730
    C2; C2 domain
  33. NM_001394464.1NP_001381393.1  synaptotagmin-like protein 2 isoform bb

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:742898
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:602729
    C2; C2 domain
  34. NM_001394465.1NP_001381394.1  synaptotagmin-like protein 2 isoform cc

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:728884
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:645717
    C2; C2 domain
  35. NM_001394466.1NP_001381395.1  synaptotagmin-like protein 2 isoform dd

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:721877
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:581708
    C2; C2 domain
  36. NM_001394467.1NP_001381396.1  synaptotagmin-like protein 2 isoform ee

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:719875
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:579706
    C2; C2 domain
  37. NM_001394468.1NP_001381397.1  synaptotagmin-like protein 2 isoform ff

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:718874
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:578705
    C2; C2 domain
  38. NM_001394469.1NP_001381398.1  synaptotagmin-like protein 2 isoform gg

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:711867
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:571698
    C2; C2 domain
  39. NM_001394470.1NP_001381399.1  synaptotagmin-like protein 2 isoform hh

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:704860
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:586691
    C2; C2 domain
  40. NM_001394471.1NP_001381400.1  synaptotagmin-like protein 2 isoform ii

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:686842
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:603675
    C2; C2 domain
  41. NM_001394472.1NP_001381401.1  synaptotagmin-like protein 2 isoform ii

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (2) summary
    cd04020
    Location:686842
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:603675
    C2; C2 domain
  42. NM_001394473.1NP_001381402.1  synaptotagmin-like protein 2 isoform jj

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:20472203
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:19072034
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  43. NM_032943.5NP_116561.1  synaptotagmin-like protein 2 isoform a

    See identical proteins and their annotated locations for NP_116561.1

    Status: REVIEWED

    Source sequence(s)
    AB046817, AK124754, DC348081, EU035829
    Consensus CDS
    CCDS31649.1
    UniProtKB/Swiss-Prot
    Q9HCH5
    Related
    ENSP00000374610.4, ENST00000389960.8
    Conserved Domains (3) summary
    cd04020
    Location:745901
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:605732
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  44. NM_206927.4NP_996810.2  synaptotagmin-like protein 2 isoform c

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:20742230
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:19342061
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  45. NM_206928.4NP_996811.2  synaptotagmin-like protein 2 isoform d

    Status: REVIEWED

    Source sequence(s)
    AP000642, AP000974
    Conserved Domains (3) summary
    cd04020
    Location:20572213
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:19172044
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  46. NM_206929.4NP_996812.1  synaptotagmin-like protein 2 isoform b

    See identical proteins and their annotated locations for NP_996812.1

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Consensus CDS
    CCDS31652.1
    UniProtKB/Swiss-Prot
    Q9HCH5
    Related
    ENSP00000435855.1, ENST00000529581.5
    Conserved Domains (2) summary
    cd04020
    Location:211367
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:71198
    C2; C2 domain
  47. NM_206930.4NP_996813.1  synaptotagmin-like protein 2 isoform f

    See identical proteins and their annotated locations for NP_996813.1

    Status: REVIEWED

    Source sequence(s)
    AP000642
    Consensus CDS
    CCDS41698.1
    UniProtKB/Swiss-Prot
    Q9HCH5
    Related
    ENSP00000374608.3, ENST00000389958.7
    Conserved Domains (2) summary
    cd04020
    Location:200356
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:60187
    C2; C2 domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    85694229..85854870 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017017934.1XP_016873423.1  synaptotagmin-like protein 2 isoform X6

  2. XM_011545109.2XP_011543411.1  synaptotagmin-like protein 2 isoform X8

    Conserved Domains (2) summary
    cd04020
    Location:20252181
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:18852012
    C2; C2 domain
  3. XM_005274066.1XP_005274123.1  synaptotagmin-like protein 2 isoform X17

    Conserved Domains (3) summary
    cd04020
    Location:729885
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:589716
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  4. XM_017017935.1XP_016873424.1  synaptotagmin-like protein 2 isoform X10

  5. XM_011545108.1XP_011543410.1  synaptotagmin-like protein 2 isoform X7

    Conserved Domains (3) summary
    cd04020
    Location:20342190
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:18942021
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  6. XM_011545110.1XP_011543412.1  synaptotagmin-like protein 2 isoform X9

    Conserved Domains (3) summary
    cd04020
    Location:20172173
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:19342006
    C2; C2 domain
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily
  7. XM_017017936.1XP_016873425.1  synaptotagmin-like protein 2 isoform X11

    Related
    ENST00000525423.5
  8. XM_017017939.1XP_016873428.1  synaptotagmin-like protein 2 isoform X20

  9. XM_011545116.2XP_011543418.1  synaptotagmin-like protein 2 isoform X24

    See identical proteins and their annotated locations for XP_011543418.1

    Conserved Domains (2) summary
    cd04020
    Location:160316
    C2B_SLP_1-2-3-4; C2 domain second repeat present in Synaptotagmin-like proteins 1-4
    cl14603
    Location:20147
    C2; C2 domain
  10. XM_011545112.1XP_011543414.1  synaptotagmin-like protein 2 isoform X12

    Conserved Domains (1) summary
    cl22851
    Location:541
    PHD_SF; PHD finger superfamily

RNA

  1. XR_001747912.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_017695.1: Suppressed sequence

    Description
    NM_017695.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
  2. NM_032379.3: Suppressed sequence

    Description
    NM_032379.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
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