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BRCA1 BRCA1 DNA repair associated [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 554178, updated on 24-Jun-2020

Summary

Gene symbol
BRCA1
Gene description
BRCA1 DNA repair associated
See related
Ensembl:ENSMODG00000015150
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
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Genomic context

See BRCA1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
23
Annotation release Status Assembly Chr Location
103 current MonDom5 (GCF_000002295.2) 2 NC_008802.1 (193075219..193152046)

Chromosome 2 - NC_008802.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 106A Neighboring gene NBR1 autophagy cargo receptor Neighboring gene uncharacterized LOC103105964 Neighboring gene Rho family GTPase 2 Neighboring gene vesicle amine transport 1

Genomic regions, transcripts, and products

Genomic Sequence:
NC_008802.1 Chromosome 2 Reference MonDom5 Primary Assembly

General protein information

Preferred Names
breast cancer type 1 susceptibility protein
Names
breast cancer 1, early onset
breast cancer susceptibility protein
NP_001029141.1
XP_007482190.1
XP_007482191.1
XP_016284352.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033969.1NP_001029141.1  breast cancer type 1 susceptibility protein

    Status: PROVISIONAL

    Source sequence(s)
    AY994160
    UniProtKB/TrEMBL
    Q52P67
    Related
    ENSMODP00000018933.2, ENSMODT00000019275.2
    Conserved Domains (6) summary
    smart00292
    Location:17351819
    BRCT; breast cancer carboxy-terminal domain
    cd00162
    Location:2368
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam00533
    Location:16341700
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam04747
    Location:13181585
    DUF612; Protein of unknown function, DUF612
    pfam12820
    Location:340507
    BRCT_assoc; Serine-rich domain associated with BRCT
    cl21456
    Location:489550
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

RefSeqs of Annotated Genomes: Monodelphis domestica Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MonDom5 Primary Assembly

Genomic

  1. NC_008802.1 Reference MonDom5 Primary Assembly

    Range
    193075219..193152046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007482128.2XP_007482190.1  breast cancer type 1 susceptibility protein isoform X1

    UniProtKB/TrEMBL
    F7CFT5
    Conserved Domains (5) summary
    smart00292
    Location:17351819
    BRCT; breast cancer carboxy-terminal domain
    cd00162
    Location:2368
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam00533
    Location:16341700
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam04747
    Location:13181585
    DUF612; Protein of unknown function, DUF612
    pfam12820
    Location:340507
    BRCT_assoc; Serine-rich domain associated with BRCT
  2. XM_007482129.2XP_007482191.1  breast cancer type 1 susceptibility protein isoform X2

    Conserved Domains (4) summary
    smart00292
    Location:17331817
    BRCT; breast cancer carboxy-terminal domain
    cd00162
    Location:2368
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam00533
    Location:16321698
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12820
    Location:340507
    BRCT_assoc; Serine-rich domain associated with BRCT
  3. XM_016428866.1XP_016284352.1  breast cancer type 1 susceptibility protein isoform X1

    UniProtKB/TrEMBL
    F7CFT5
    Conserved Domains (5) summary
    smart00292
    Location:17351819
    BRCT; breast cancer carboxy-terminal domain
    cd00162
    Location:2368
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam00533
    Location:16341700
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam04747
    Location:13181585
    DUF612; Protein of unknown function, DUF612
    pfam12820
    Location:340507
    BRCT_assoc; Serine-rich domain associated with BRCT