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lgals3a lectin, galactoside binding soluble 3a [ Danio rerio (zebrafish) ]

Gene ID: 557373, updated on 29-May-2021

Summary

Official Symbol
lgals3aprovided by ZNC
Official Full Name
lectin, galactoside binding soluble 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7667
See related
Ensembl:ENSDARG00000077850
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
lgals3; fb13c09; fk60g08; si:ch211-67f24.5
Orthologs
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Genomic context

See lgals3a in Genome Data Viewer
Location:
chromosome: 13
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (36568633..36582393, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (36442803..36456562, complement)
103 previous assembly Zv9 (GCF_000002035.4) 13 NC_007124.5 (36970500..36984279, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene desumoylating isopeptidase 2-like Neighboring gene synaptojanin 2 binding protein Neighboring gene glia maturation factor, beta Neighboring gene cornichon family AMPA receptor auxiliary protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables IgE binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables IgE binding IEA
Inferred from Electronic Annotation
more info
 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables laminin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in eosinophil chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within innate immune response IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in macrophage chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in monocyte chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in neutrophil chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of calcium ion import IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in immunological synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
galectin-3; basic proline-rich protein
Names
lectin, galactoside-binding, soluble, 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386796.1NP_001373725.1  galectin-3 isoform 1

    Status: VALIDATED

    Source sequence(s)
    BX927407
    Conserved Domains (2) summary
    smart00908
    Location:246362
    Gal-bind_lectin; Galactoside-binding lectin
    PRK07764
    Location:11158
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
  2. NM_001386797.1NP_001373726.1  galectin-3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    BX927407
    Conserved Domains (1) summary
    PRK07764
    Location:26241
    PRK07764; DNA polymerase III subunits gamma and tau; Validated

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    36568633..36582393 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_699180.9XP_704272.2  galectin-3 isoform X1

    Related
    ENSDARP00000100661.3, ENSDART00000113204.4
    Conserved Domains (2) summary
    smart00908
    Location:246362
    Gal-bind_lectin; Galactoside-binding lectin
    PRK07764
    Location:11158
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
  2. XM_005157026.3XP_005157083.1  basic proline-rich protein isoform X2

    Conserved Domains (1) summary
    PRK07764
    Location:26241
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
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