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Slc1a4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 [ Mus musculus (house mouse) ]

Gene ID: 55963, updated on 23-Jun-2021

Summary

Official Symbol
Slc1a4provided by MGI
Official Full Name
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4provided by MGI
Primary source
MGI:MGI:2135601
See related
Ensembl:ENSMUSG00000020142
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ASC; SATT; ASCT1; ASCT-1; AW045657
Expression
Ubiquitous expression in CNS E18 (RPKM 12.1), whole brain E14.5 (RPKM 9.3) and 25 other tissues See more
Orthologs
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Genomic context

See Slc1a4 in Genome Data Viewer
Location:
11 A3.1; 11 12.97 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (20252180..20282713, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (20302180..20332713, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (20202183..20232716, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene centrosomal protein 68 Neighboring gene predicted gene, 39604 Neighboring gene ribosomal proteimn L12-ps2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 39605

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in L-alanine import across plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in L-alanine transport ISO
Inferred from Sequence Orthology
more info
 
involved_in L-aspartate import across plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
involved_in L-serine import across plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in L-serine transport ISO
Inferred from Sequence Orthology
more info
 
involved_in cognition ISO
Inferred from Sequence Orthology
more info
 
involved_in hydroxyproline transport ISO
Inferred from Sequence Orthology
more info
 
involved_in proline transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within serine import across plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
involved_in threonine transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in intermediate filament IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
neutral amino acid transporter A
Names
alanine/serine/cysteine/threonine transporter 1
solute carrier family 1 member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018861.3NP_061349.3  neutral amino acid transporter A

    See identical proteins and their annotated locations for NP_061349.3

    Status: VALIDATED

    Source sequence(s)
    AK140866, BC052733
    Consensus CDS
    CCDS24457.1
    UniProtKB/Swiss-Prot
    O35874
    UniProtKB/TrEMBL
    Q3US35, Q3UTP8
    Related
    ENSMUSP00000105223.2, ENSMUST00000109594.8
    Conserved Domains (1) summary
    pfam00375
    Location:44477
    SDF; Sodium:dicarboxylate symporter family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    20252180..20282713 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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