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slc31a2 solute carrier family 31 member 2 [ Danio rerio (zebrafish) ]

Gene ID: 563012, updated on 27-Mar-2024

Summary

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Official Symbol
slc31a2provided by ZNC
Official Full Name
solute carrier family 31 member 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030925-25
See related
Ensembl:ENSDARG00000076092 AllianceGenome:ZFIN:ZDB-GENE-030925-25
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:cb797; si:ch211-282j22.4
Summary
Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in cellular copper ion homeostasis. Predicted to act upstream of or within copper ion transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in hatching gland and polster. Orthologous to human SLC31A2 (solute carrier family 31 member 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (13785960..13796940)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (13689238..13700211)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene neural proliferation, differentiation and control, 1a Neighboring gene si:ch211-282j22.3 Neighboring gene niban apoptosis regulator 2a Neighboring gene syntaxin binding protein 1a Neighboring gene uncharacterized LOC103909432

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Expression and regulation of drug transporters in vertebrate neutrophils. Foulkes MJ, et al. Sci Rep, 2017 Jul 10. PMID 28694436, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables copper ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within copper ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within copper ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
probable low affinity copper uptake protein 2
Names
solute carrier family 31 (copper transporter), member 2
solute carrier family 31 (copper transporters), member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198749.1 → NP_001185678.1  probable low affinity copper uptake protein 2

    Status: VALIDATED

    Source sequence(s)
    BC122215
    UniProtKB/TrEMBL
    A0A8M1NW97, E9QC64
    Related
    ENSDARP00000121272.1, ENSDART00000134682.2
    Conserved Domains (1) summary
    pfam04145
    Location:116 → 163
    Ctr; Ctr copper transporter family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    13785960..13796940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009295248.3 → XP_009293523.1  probable low affinity copper uptake protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AM17
    Conserved Domains (1) summary
    pfam04145
    Location:114 → 161
    Ctr; Ctr copper transporter family

  2. XM_009295247.3 → XP_009293522.1  probable low affinity copper uptake protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M3B4K8
    Conserved Domains (1) summary
    pfam04145
    Location:116 → 163
    Ctr; Ctr copper transporter family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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