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Eif3c eukaryotic translation initiation factor 3, subunit C [ Mus musculus (house mouse) ]

Gene ID: 56347, updated on 23-Jun-2021

Summary

Official Symbol
Eif3cprovided by MGI
Official Full Name
eukaryotic translation initiation factor 3, subunit Cprovided by MGI
Primary source
MGI:MGI:1926966
See related
Ensembl:ENSMUSG00000030738
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
X; Xs; NIP; Xsl; Eif3; 110kD; 110kDa; Eif3s8; NipilA3; NIPIL(A3); 3230401O13Rik
Expression
Ubiquitous expression in testis adult (RPKM 75.2), placenta adult (RPKM 74.3) and 28 other tissues See more
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Genomic context

See Eif3c in Genome Data Viewer
Location:
7 69.14 cM; 7 F3
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126146083..126165538, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (126546911..126566366, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (133690425..133709880, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene Tu translation elongation factor, mitochondrial Neighboring gene ataxin 2-like Neighboring gene RIKEN cDNA 4930456A14 gene Neighboring gene predicted gene, 24596 Neighboring gene predicted gene, 25579 Neighboring gene ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) Neighboring gene microRNA 7059

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (2) 
  • Chemically induced (ENU) (1) 
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Eif3c gene: The Eif3c gene is conserved in human, Rhesus monkey, dog, cow, rat, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Clone Names

  • MGC36637

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables ribosome binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables translation initiation factor activity IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to translation initiation factor activity ISO
Inferred from Sequence Orthology
more info
 
enables translation initiation factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in translational initiation IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
eukaryotic translation initiation factor 3 subunit C
Names
NIPI-like protein
eIF3 p110
eIF3c
eukaryotic translation initiation factor 3 subunit 8
eukaryotic translation initiation factor 3, subunit 8 (110 kDa)
extra-toes spotting

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146200.1NP_666312.1  eukaryotic translation initiation factor 3 subunit C

    See identical proteins and their annotated locations for NP_666312.1

    Status: PROVISIONAL

    Source sequence(s)
    BC024855
    Consensus CDS
    CCDS21832.1
    UniProtKB/Swiss-Prot
    Q8R1B4
    Related
    ENSMUSP00000032992.5, ENSMUST00000032992.7
    Conserved Domains (2) summary
    smart00753
    Location:776864
    PAM; PCI/PINT associated module
    pfam05470
    Location:29703
    eIF-3c_N; Eukaryotic translation initiation factor 3 subunit 8 N-terminus

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    126146083..126165538 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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