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Pdlim5 PDZ and LIM domain 5 [ Mus musculus (house mouse) ]

Gene ID: 56376, updated on 16-Oct-2021

Summary

Official Symbol
Pdlim5provided by MGI
Official Full Name
PDZ and LIM domain 5provided by MGI
Primary source
MGI:MGI:1927489
See related
Ensembl:ENSMUSG00000028273
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Enh; LIM; Enh1; Enh2; Enh3; C87059; AI987914; 1110001A05Rik
Expression
Broad expression in heart adult (RPKM 41.4), bladder adult (RPKM 16.5) and 27 other tissues See more
Orthologs
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Genomic context

See Pdlim5 in Genome Data Viewer
Location:
3; 3 H1
Exon count:
20
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (141945346..142101480, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (142239585..142395719, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (141903568..142058630, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene unc-5 netrin receptor C Neighboring gene bone morphogenetic protein receptor, type 1B Neighboring gene GABA(A) receptor-associated protein-like 2 pseudogene 3 Neighboring gene VISTA enhancer mm1018 Neighboring gene predicted gene, 33189

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables actin binding ISO
Inferred from Sequence Orthology
more info
 
enables actinin binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables muscle alpha-actinin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein N-terminus binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase C binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell growth involved in cardiac muscle cell development ISO
Inferred from Sequence Orthology
more info
 
involved_in heart development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in muscle structure development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of dendritic spine morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of synapse assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in Z disc IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Z disc IDA
Inferred from Direct Assay
more info
PubMed 
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
is_active_in adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
part_of filamentous actin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
is_active_in stress fiber IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
PDZ and LIM domain protein 5
Names
enigma homolog
enigma-like PDZ and LIM domains protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190852.1NP_001177781.1  PDZ and LIM domain protein 5 isoform ENH1e

    See identical proteins and their annotated locations for NP_001177781.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) represents the longest transcript and it encodes the longest protein (isoform ENH1e).
    Source sequence(s)
    AC139128, AC158581, AK147999, BY227455, DV551664
    Consensus CDS
    CCDS80038.1
    UniProtKB/Swiss-Prot
    Q8CI51
    UniProtKB/TrEMBL
    D9J302
    Related
    ENSMUSP00000142737.2, ENSMUST00000195975.5
    Conserved Domains (5) summary
    cd09453
    Location:438489
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15229
    Location:303413
    POM121; POM121 family
    pfam15936
    Location:105185
    DUF4749; Domain of unknown function (DUF4749)
    cl02475
    Location:556610
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  2. NM_001190853.1NP_001177782.1  PDZ and LIM domain protein 5 isoform ENH4

    See identical proteins and their annotated locations for NP_001177782.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) has multiple differences, compared to variant 4. The resulting protein (isoform ENH4) has a shorter and distinct C-terminus when compared to isoform ENH1e.
    Source sequence(s)
    AC139128, AC158581, AK009464
    Consensus CDS
    CCDS57258.1
    UniProtKB/TrEMBL
    Q9CRA2
    Related
    ENSMUSP00000087595.6, ENSMUST00000090134.12
    Conserved Domains (2) summary
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:100171
    DUF4749; Domain of unknown function (DUF4749)
  3. NM_001190854.1NP_001177783.1  PDZ and LIM domain protein 5 isoform ENH1b

    See identical proteins and their annotated locations for NP_001177783.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks three alternate exons, compared to variant 4. The resulting protein (isoform ENH1b) is shorter, compared to isoform ENH1e.
    Source sequence(s)
    AC139128, AC158581, AK147999, BY227455, DV551664
    Consensus CDS
    CCDS80035.1
    UniProtKB/Swiss-Prot
    Q8CI51
    UniProtKB/TrEMBL
    D9J2Z9
    Related
    ENSMUSP00000142899.2, ENSMUST00000198381.5
    Conserved Domains (5) summary
    PHA03381
    Location:136323
    PHA03381; tegument protein VP22; Provisional
    cd09453
    Location:306357
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105185
    DUF4749; Domain of unknown function (DUF4749)
    cl02475
    Location:424478
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  4. NM_001190855.1NP_001177784.1  PDZ and LIM domain protein 5 isoform ENH1c

    See identical proteins and their annotated locations for NP_001177784.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) lacks two alternate exons, compared to variant 4. The resulting protein (isoform ENH1c) is shorter when it is compared to isoform ENH1e.
    Source sequence(s)
    AC139128, AC158581, AK147999, BY227455, DV551664
    Consensus CDS
    CCDS80036.1
    UniProtKB/Swiss-Prot
    Q8CI51
    UniProtKB/TrEMBL
    D9J300
    Related
    ENSMUSP00000143343.2, ENSMUST00000200043.5
    Conserved Domains (5) summary
    cd09453
    Location:350401
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15229
    Location:215325
    POM121; POM121 family
    pfam15936
    Location:105185
    DUF4749; Domain of unknown function (DUF4749)
    cl02475
    Location:468522
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  5. NM_001190856.1NP_001177785.1  PDZ and LIM domain protein 5 isoform ENH1d

    See identical proteins and their annotated locations for NP_001177785.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) lacks an alternate exon, compared to variant 4. The resulting protein (isoform ENH1d) is shorter when it is compared to isoform ENH1e.
    Source sequence(s)
    AC139128, AC158581, AK147999, BY227455, DV551664
    Consensus CDS
    CCDS80037.1
    UniProtKB/Swiss-Prot
    Q8CI51
    UniProtKB/TrEMBL
    D9J301
    Related
    ENSMUSP00000142460.2, ENSMUST00000196220.5
    Conserved Domains (5) summary
    cd09453
    Location:398449
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15229
    Location:263373
    POM121; POM121 family
    pfam15936
    Location:105185
    DUF4749; Domain of unknown function (DUF4749)
    cl02475
    Location:516570
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  6. NM_001190857.1NP_001177786.1  PDZ and LIM domain protein 5 isoform ENH3a

    See identical proteins and their annotated locations for NP_001177786.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) has multiple differences in the 3' end, compared to variant 4. The resulting protein (isoform ENH3a) has a shorter and distinct C-terminus when compared to isoform ENH1e.
    Source sequence(s)
    AA061806, AC139128, BY227455, CA534475, CB597177
    Consensus CDS
    CCDS80039.1
    UniProtKB/TrEMBL
    D9J303
    Related
    ENSMUSP00000132647.4, ENSMUST00000168967.9
    Conserved Domains (2) summary
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105201
    DUF4749; Domain of unknown function (DUF4749)
  7. NM_019808.3NP_062782.2  PDZ and LIM domain protein 5 isoform ENH1

    See identical proteins and their annotated locations for NP_062782.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses a different splice site and lacks alternate segments, compared to variant 4. The resulting protein (isoform ENH1) is shorter when it is compared to isoform ENH1e. This isoform has also been called ENH1/1a.
    Source sequence(s)
    AC139128, AC158581, AK147999, BY227455, DV551664
    Consensus CDS
    CCDS17875.1
    UniProtKB/Swiss-Prot
    Q8CI51
    Related
    ENSMUSP00000029941.10, ENSMUST00000029941.16
    Conserved Domains (5) summary
    cd09453
    Location:415466
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15741
    Location:75388
    LRIF1; Ligand-dependent nuclear receptor-interacting factor 1
    pfam15936
    Location:214294
    DUF4749; Domain of unknown function (DUF4749)
    cl02475
    Location:533587
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  8. NM_019809.3NP_062783.2  PDZ and LIM domain protein 5 isoform ENH2

    See identical proteins and their annotated locations for NP_062783.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different splice site and has multiple differences in the 3' end, compared to variant 4. The resulting protein (isoform ENH2) is shorter and has a distinct C-terminus when it is compared to isoform ENH1e.
    Source sequence(s)
    AC139128, AC158581, AI391027, AK009464, BY227455, BY741234
    Consensus CDS
    CCDS17876.1
    UniProtKB/TrEMBL
    Q9CRA2
    Related
    ENSMUSP00000143098.2, ENSMUST00000196908.5
    Conserved Domains (2) summary
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214294
    DUF4749; Domain of unknown function (DUF4749)
  9. NM_022554.3NP_072048.2  PDZ and LIM domain protein 5 isoform ENH3b

    See identical proteins and their annotated locations for NP_072048.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has multiple differences, compared to variant 4. The resulting protein (isoform ENH3b) has a shorter and distinct C-terminus when it is compared to isoform ENH1e. The encoded isoform was previously known as ENH3b.
    Source sequence(s)
    AA512794, AC139128, BY227455, CA534475
    Consensus CDS
    CCDS38656.1
    UniProtKB/TrEMBL
    E9Q8P5
    Related
    ENSMUSP00000128752.3, ENSMUST00000170361.9
    Conserved Domains (2) summary
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105206
    DUF4749; Domain of unknown function (DUF4749)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    141945346..142101480 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319659.2XP_017175148.1  PDZ and LIM domain protein 5 isoform X11

    Conserved Domains (4) summary
    cd09453
    Location:424475
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02475
    Location:542596
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam15936
    Location:115181
    DUF4749; Domain of unknown function (DUF4749)
  2. XM_036163173.1XP_036019066.1  PDZ and LIM domain protein 5 isoform X14

    Conserved Domains (4) summary
    cd09453
    Location:354405
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105195
    DUF4749; Domain of unknown function (DUF4749)
    cl02475
    Location:472526
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  3. XM_006501748.2XP_006501811.1  PDZ and LIM domain protein 5 isoform X15

    Conserved Domains (5) summary
    PHA03381
    Location:132329
    PHA03381; tegument protein VP22; Provisional
    cd09453
    Location:312363
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02475
    Location:430484
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam15936
    Location:105201
    DUF4749; Domain of unknown function (DUF4749)
  4. XM_036163172.1XP_036019065.1  PDZ and LIM domain protein 5 isoform X13

    Conserved Domains (4) summary
    cd09453
    Location:360411
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105201
    DUF4749; Domain of unknown function (DUF4749)
    cl02475
    Location:478532
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  5. XM_006501745.2XP_006501808.1  PDZ and LIM domain protein 5 isoform X9

    Conserved Domains (4) summary
    cd09453
    Location:444495
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02475
    Location:562616
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam15936
    Location:105201
    DUF4749; Domain of unknown function (DUF4749)
  6. XM_006501744.2XP_006501807.1  PDZ and LIM domain protein 5 isoform X8

    Conserved Domains (5) summary
    cd09453
    Location:449500
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:508559
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02475
    Location:567621
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam15936
    Location:105206
    DUF4749; Domain of unknown function (DUF4749)
  7. XM_036163170.1XP_036019063.1  PDZ and LIM domain protein 5 isoform X6

    Conserved Domains (5) summary
    cd09453
    Location:507558
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:566617
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:625679
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214304
    DUF4749; Domain of unknown function (DUF4749)
  8. XM_006501740.2XP_006501803.1  PDZ and LIM domain protein 5 isoform X3

    Conserved Domains (5) summary
    cd09453
    Location:547598
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:606657
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:665719
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214304
    DUF4749; Domain of unknown function (DUF4749)
  9. XM_036163171.1XP_036019064.1  PDZ and LIM domain protein 5 isoform X12

    Conserved Domains (5) summary
    cd09453
    Location:421472
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:539593
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    PHA03307
    Location:82403
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02475
    Location:480531
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  10. XM_006501739.2XP_006501802.1  PDZ and LIM domain protein 5 isoform X2

    Conserved Domains (5) summary
    cd09453
    Location:553604
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:612663
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:671725
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214310
    DUF4749; Domain of unknown function (DUF4749)
  11. XM_006501746.2XP_006501809.1  PDZ and LIM domain protein 5 isoform X10

    Conserved Domains (5) summary
    cd09453
    Location:426477
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:544598
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    PHA03307
    Location:82408
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02475
    Location:485536
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  12. XM_006501743.2XP_006501806.1  PDZ and LIM domain protein 5 isoform X7

    Conserved Domains (6) summary
    cd09453
    Location:474525
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:533584
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:592646
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    PRK12323
    Location:79274
    PRK12323; DNA polymerase III subunit gamma/tau
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214315
    DUF4749; Domain of unknown function (DUF4749)
  13. XM_006501741.2XP_006501804.1  PDZ and LIM domain protein 5 isoform X4

    Conserved Domains (6) summary
    cd09453
    Location:518569
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:577628
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:636690
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    PHA03307
    Location:150537
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214315
    DUF4749; Domain of unknown function (DUF4749)
  14. XM_006501742.2XP_006501805.1  PDZ and LIM domain protein 5 isoform X5

    Conserved Domains (6) summary
    cd09453
    Location:514565
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:573624
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:632686
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    PHA03307
    Location:150533
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214315
    DUF4749; Domain of unknown function (DUF4749)
  15. XM_006501738.2XP_006501801.1  PDZ and LIM domain protein 5 isoform X1

    Conserved Domains (6) summary
    cd09453
    Location:558609
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:617668
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:676730
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    PHA03307
    Location:150540
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214315
    DUF4749; Domain of unknown function (DUF4749)
  16. XM_006501751.4XP_006501814.1  PDZ and LIM domain protein 5 isoform X17

    See identical proteins and their annotated locations for XP_006501814.1

    UniProtKB/TrEMBL
    D9J303
    Related
    ENSMUSP00000059267.9, ENSMUST00000058626.9
    Conserved Domains (2) summary
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105201
    DUF4749; Domain of unknown function (DUF4749)
  17. XM_006501750.4XP_006501813.1  PDZ and LIM domain protein 5 isoform X16

    See identical proteins and their annotated locations for XP_006501813.1

    UniProtKB/TrEMBL
    E9Q8P5
    Conserved Domains (2) summary
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105206
    DUF4749; Domain of unknown function (DUF4749)
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