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Tspan6 tetraspanin 6 [ Mus musculus (house mouse) ]

Gene ID: 56496, updated on 23-Jun-2021

Summary

Official Symbol
Tspan6provided by MGI
Official Full Name
tetraspanin 6provided by MGI
Primary source
MGI:MGI:1926264
See related
Ensembl:ENSMUSG00000067377
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
T245; Tm4sf; Tm4sf6; TSPAN-6; AI316786; 6720473L21Rik
Expression
Broad expression in CNS E18 (RPKM 40.5), whole brain E14.5 (RPKM 35.2) and 18 other tissues See more
Orthologs
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Genomic context

See Tspan6 in Genome Data Viewer
Location:
X; X E3
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (132791817..132801957, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (133891068..133901208, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (130425609..130432968, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene protocadherin 19 Neighboring gene predicted gene, 26851 Neighboring gene tenomodulin Neighboring gene sushi-repeat-containing protein, X-linked 2 Neighboring gene synaptotagmin-like 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Clone Names

  • MGC117923

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tetraspanin-6
Names
tetraspan TM4SF
transmembrane 4 superfamily member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019656.3NP_062630.2  tetraspanin-6

    See identical proteins and their annotated locations for NP_062630.2

    Status: VALIDATED

    Source sequence(s)
    AA458002, AK167384, AV351536
    Consensus CDS
    CCDS30387.1
    UniProtKB/TrEMBL
    Q99L96
    Related
    ENSMUSP00000084838.6, ENSMUST00000087557.12
    Conserved Domains (1) summary
    pfam00335
    Location:17233
    Tetraspannin; Tetraspanin family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    132791817..132801957 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030251428.1XP_030107288.1  tetraspanin-6 isoform X1

    Conserved Domains (1) summary
    pfam00335
    Location:17233
    Tetraspannin; Tetraspanin family
  2. XM_036162050.1XP_036017943.1  tetraspanin-6 isoform X2

    Conserved Domains (1) summary
    cd03161
    Location:24121
    TM4SF2_6_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
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