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Cib2 calcium and integrin binding family member 2 [ Mus musculus (house mouse) ]

Gene ID: 56506, updated on 27-Jul-2021

Summary

Official Symbol
Cib2provided by MGI
Official Full Name
calcium and integrin binding family member 2provided by MGI
Primary source
MGI:MGI:1929293
See related
Ensembl:ENSMUSG00000037493
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
KIP2; KIP 2; AI449053; 2810434I23Rik
Expression
Broad expression in subcutaneous fat pad adult (RPKM 48.8), mammary gland adult (RPKM 40.3) and 19 other tissues See more
Orthologs
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Genomic context

See Cib2 in Genome Data Viewer
Location:
9; 9 A5.3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (54452074..54467512, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (54544794..54560190, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (54393159..54407886, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene gliomedin, opposite strand Neighboring gene gliomedin Neighboring gene Dmx-like 2 Neighboring gene SH2 domain containing 7 Neighboring gene isocitrate dehydrogenase 3 (NAD+) alpha Neighboring gene acyl-CoA synthetase bubblegum family member 1 Neighboring gene predicted gene, 51677

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables calcium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables integrin binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables protein-containing complex binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cellular response to ATP ISO
Inferred from Sequence Orthology
more info
 
involved_in photoreceptor cell maintenance IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cuticular plate ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in muscle tendon junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in neuromuscular junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in photoreceptor inner segment IDA
Inferred from Direct Assay
more info
PubMed 
located_in photoreceptor outer segment IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in sarcolemma IDA
Inferred from Direct Assay
more info
PubMed 
located_in stereocilium IDA
Inferred from Direct Assay
more info
PubMed 
located_in stereocilium ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
calcium and integrin-binding family member 2
Names
calcium binding protein Kip2
kinase-interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019686.6NP_062660.1  calcium and integrin-binding family member 2

    See identical proteins and their annotated locations for NP_062660.1

    Status: VALIDATED

    Source sequence(s)
    AB016080, AI842389, AK013240, DN175059
    Consensus CDS
    CCDS40642.1
    UniProtKB/Swiss-Prot
    Q9Z309
    UniProtKB/TrEMBL
    Q544Z8
    Related
    ENSMUSP00000038527.7, ENSMUST00000041901.7
    Conserved Domains (1) summary
    COG5126
    Location:68178
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    54452074..54467512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155147.1XP_036011040.1  calcium and integrin-binding family member 2 isoform X1

    Conserved Domains (1) summary
    COG5126
    Location:25135
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
  2. XM_036155148.1XP_036011041.1  calcium and integrin-binding family member 2 isoform X1

    Conserved Domains (1) summary
    COG5126
    Location:25135
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
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