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sik2b salt-inducible kinase 2b [ Danio rerio (zebrafish) ]

Gene ID: 567919, updated on 27-Mar-2024

Summary

Official Symbol
sik2bprovided by ZNC
Official Full Name
salt-inducible kinase 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-071012-1
See related
Ensembl:ENSDARG00000062315 AllianceGenome:ZFIN:ZDB-GENE-071012-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
snf1lk2b
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cellular response to glucose starvation; intracellular signal transduction; and protein phosphorylation. Predicted to be active in cytoplasm. Orthologous to human SIK2 (salt inducible kinase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 15
Exon count:
15
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (21781764..21837001, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (21846033..21901271, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene NKAP domain containing 1 Neighboring gene protein phosphatase 2, regulatory subunit A, beta b Neighboring gene layilin b Neighboring gene zona pellucida-like domain-containing protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
serine/threonine-protein kinase SIK2
Names
SNF1-like kinase 2b
XP_696325.5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    21781764..21837001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_691233.8XP_696325.5  serine/threonine-protein kinase SIK2

    UniProtKB/TrEMBL
    A0A8N7URB1, E7F378
    Related
    ENSDARP00000084386.4, ENSDART00000089953.6
    Conserved Domains (3) summary
    smart00220
    Location:22273
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14409
    Location:299343
    UBA_SIK2; UBA domain found in salt-inducible kinase 2 (SIK2)
    cd14071
    Location:21273
    STKc_SIK; Catalytic domain of the Serine/Threonine Kinases, Salt-Inducible kinases