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Pp1-Y1 Protein phosphatase 1, Y-linked 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 5740113, updated on 29-Dec-2023

Summary

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Official Symbol
Pp1-Y1provided by FlyBase
Official Full Name
Protein phosphatase 1, Y-linked 1provided by FlyBase
Primary source
FLYBASE:FBgn0261399
Locus tag
Dmel_CG41534
See related
AllianceGenome:FB:FBgn0261399
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG41534; Dmel\CG41534; DmPp1-Y1; Pp1Y1
Summary
Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in cyst cell of testis; organism; and testis. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: Y
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) Y NC_024512.1 (9833..10786)

Chromosome Y - NC_024512.1Genomic Context describing neighboring genes Neighboring gene male fertility factor kl5 Neighboring gene polycystine-related-Y

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024512.1 Chromosome Y Reference Release 6 plus ISO1 MT Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of five new genes on the Y chromosome of Drosophila melanogaster. Carvalho AB, et al. Proc Natl Acad Sci U S A, 2001 Nov 6. PMID 11687639, Free PMC Article
  2. Drosophila melanogaster Y Chromosome Genes Affect Male Sensitivity to Microbial Infections. Bartolo G, et al. Insects, 2021 Jan 5. PMID 33466347, Free PMC Article
  3. Positive and purifying selection on the Drosophila Y chromosome. Singh ND, et al. Mol Biol Evol, 2014 Oct. PMID 24974375, Free PMC Article
  4. Unique structure and positive selection promote the rapid divergence of Drosophila Y chromosomes. Chang CH, et al. Elife, 2022 Jan 6. PMID 34989337, Free PMC Article
  5. The Role of Y Chromosome Genes in Male Fertility in Drosophila melanogaster. Zhang J, et al. Genetics, 2020 Jul. PMID 32404399, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

  • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein phosphatase 1, Y-linked 1
Names
CG41534-PC
Pp1-Y1-PC
NP_001104152.3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_024512.1 Reference assembly

    Range
    9833..10786
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001110682.3 → NP_001104152.3  protein phosphatase 1, Y-linked 1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001104152.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8QI94, Q95V52
    Conserved Domains (2) summary
    smart00156
    Location:36 → 305
    PP2Ac; Protein phosphatase 2A homologues, catalytic domain
    cl13995
    Location:17 → 303
    MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8QI94 A8QI94
Q95V52 Q95V52

Gene LinkOut

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