U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

FAS Fas cell surface death receptor [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 574332, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
FASprovided by VGNC
Official Full Name
Fas cell surface death receptorprovided by VGNC
Primary source
VGNC:VGNC:72479
See related
Ensembl:ENSMMUG00000009339
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
CD95
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See FAS in Genome Data Viewer
Location:
chromosome: 9
Exon count:
10
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (89258065..89283471)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (84174170..84199616)

Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene STAM binding protein like 1 Neighboring gene actin alpha 2, smooth muscle Neighboring gene small nucleolar RNA U13 Neighboring gene zinc finger RNA-binding protein pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Fas and FasL expression in the spinal cord following cord hemisection in the monkey. Jia L, et al. Neurochem Res, 2011 Mar. PMID 21181266
  2. Cloning, sequencing, and homology analysis of nonhuman primate Fas/Fas-ligand and co-stimulatory molecules. Villinger F, et al. Immunogenetics, 2001 May-Jun. PMID 11491535

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tumor necrosis factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation-induced cell death of T cells IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in motor neuron apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in necroptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of stress-activated MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of CD95 death-inducing signaling complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
tumor necrosis factor receptor superfamily member 6
Names
FASLG receptor
Fas (TNF receptor superfamily, member 6)
Fas receptor CD95
apo-1 antigen
apoptosis-mediating surface antigen FAS

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032933.2 → NP_001028105.1  tumor necrosis factor receptor superfamily member 6 precursor

    See identical proteins and their annotated locations for NP_001028105.1

    Status: PROVISIONAL

    Source sequence(s)
    AF344833
    UniProtKB/Swiss-Prot
    Q9BDP2
    UniProtKB/TrEMBL
    F6V1W6, H9Z8J8
    Related
    ENSMMUP00000014651.3, ENSMMUT00000015642.4
    Conserved Domains (2) summary
    cd08316
    Location:224 → 317
    Death_FAS_TNFRSF6; Death domain of FAS or TNF receptor superfamily member 6
    cd10579
    Location:39 → 167
    TNFRSF6; Tumor necrosis factor receptor superfamily member 6 (TNFRSF6), also known as fas cell surface death receptor (Fas)

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041762.1 Reference Mmul_10 Primary Assembly

    Range
    89258065..89283471
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015147623.2 → XP_015003109.2  tumor necrosis factor receptor superfamily member 6 isoform X3

    UniProtKB/TrEMBL
    F6V1W6, H9Z8J8
    Conserved Domains (2) summary
    cd08316
    Location:201 → 294
    Death_FAS_TNFRSF6; Death domain of FAS or TNF receptor superfamily member 6
    cd10579
    Location:39 → 167
    TNFRSF6; Tumor necrosis factor receptor superfamily member 6 (TNFRSF6), also known as fas cell surface death receptor (Fas)

  2. XM_015147622.2 → XP_015003108.2  tumor necrosis factor receptor superfamily member 6 isoform X2

    UniProtKB/TrEMBL
    F6V1W6, H9Z8J8
    Conserved Domains (2) summary
    cd08316
    Location:221 → 314
    Death_FAS_TNFRSF6; Death domain of FAS or TNF receptor superfamily member 6
    cd10579
    Location:59 → 187
    TNFRSF6; Tumor necrosis factor receptor superfamily member 6 (TNFRSF6), also known as fas cell surface death receptor (Fas)

  3. XM_015147621.2 → XP_015003107.2  tumor necrosis factor receptor superfamily member 6 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R6H4, F6V1W6, H9Z8J8
    Related
    ENSMMUP00000055912.2, ENSMMUT00000055497.2
    Conserved Domains (2) summary
    cd08316
    Location:244 → 337
    Death_FAS_TNFRSF6; Death domain of FAS or TNF receptor superfamily member 6
    cd10579
    Location:59 → 187
    TNFRSF6; Tumor necrosis factor receptor superfamily member 6 (TNFRSF6), also known as fas cell surface death receptor (Fas)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9BDP2.1 GenPept UniProtKB/Swiss-Prot:Q9BDP2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.