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CFTR CF transmembrane conductance regulator [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 574346, updated on 5-Mar-2024

Summary

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Official Symbol
CFTRprovided by VGNC
Official Full Name
CF transmembrane conductance regulatorprovided by VGNC
Primary source
VGNC:VGNC:71020
See related
Ensembl:ENSMMUG00000011269
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
ABCC7
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
27
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (143689225..143868872)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (143121867..143302744)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat, SAM and basic leucine zipper domain containing 1 Neighboring gene ankyrin repeat domain-containing protein 49-like Neighboring gene cortactin binding protein 2 Neighboring gene serine/arginine-rich splicing factor 3 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genomic DNA sequence of Rhesus (M. mulatta) cystic fibrosis (CFTR) gene. Wine JJ, et al. Mamm Genome, 1998 Apr. PMID 9530627
  2. A cross-species analysis of the cystic fibrosis transmembrane conductance regulator. Potential functional domains and regulatory sites. Diamond G, et al. J Biol Chem, 1991 Nov 25. PMID 1719001

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chloride channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bicarbonate transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chloride transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cystic fibrosis transmembrane conductance regulator
Names
ATP-binding cassette sub-family C member 7
ATP-binding cassette transporter sub-family C member 7
cAMP-dependent chloride channel
channel conductance-controlling ATPase
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
NP_001028110.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032938.1 → NP_001028110.1  cystic fibrosis transmembrane conductance regulator

    See identical proteins and their annotated locations for NP_001028110.1

    Status: PROVISIONAL

    Source sequence(s)
    AF013753
    UniProtKB/Swiss-Prot
    O62668, O62673, Q00553
    Related
    ENSMMUP00000014766.2, ENSMMUT00000015762.4
    Conserved Domains (5) summary
    cd03289
    Location:1209 → 1481
    ABCC_CFTR2; ATP-binding cassette domain 2 of CFTR,subfamily C
    cd03291
    Location:389 → 670
    ABCC_CFTR1; ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C
    TIGR01271
    Location:1 → 1481
    CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
    pfam00664
    Location:866 → 1147
    ABC_membrane; ABC transporter transmembrane region
    pfam14396
    Location:639 → 849
    CFTR_R; Cystic fibrosis TM conductance regulator (CFTR), regulator domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    143689225..143868872
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q00553.2 GenPept UniProtKB/Swiss-Prot:Q00553

Gene LinkOut

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Molecular Biology Databases
Research Materials
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