These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001199417.2 → NP_001186346.1  rho GTPase-activating protein 23

   See identical proteins and their annotated locations for NP_001186346.1

   Status: VALIDATED

   Source sequence(s)

   AC244153

   Consensus CDS

   CCDS56027.1

   UniProtKB/Swiss-Prot

   Q9P227

   UniProtKB/TrEMBL

   A0A2X0SFL7

   Related

   ENSP00000481862.1, ENST00000622683.5

   Conserved Domains (4) summary

   cd00992
   Location:41 → 151

   PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

   cd04395
   Location:902 → 1097

   RhoGAP_ARHGAP21; RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the ...

   cd01253
   Location:690 → 810

   PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

   pfam00169
   Location:689 → 808

   PH; PH domain

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference GRCh38.p14 Primary Assembly

Genomic

1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

   Range

   38419275..38512385

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_006721991.2 → XP_006722054.1  rho GTPase-activating protein 23 isoform X2

   See identical proteins and their annotated locations for XP_006722054.1

   UniProtKB/TrEMBL

   A0A2X0SFL7, A0A9L9PXQ2

   Related

   ENSP00000516484.1, ENST00000633445.2

   Conserved Domains (4) summary

   cd00992
   Location:23 → 133

   PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

   cd04395
   Location:884 → 1079

   RhoGAP_ARHGAP21; RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the ...

   cd01253
   Location:672 → 792

   PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

   pfam00169
   Location:671 → 790

   PH; PH domain

2. XM_006721993.4 → XP_006722056.1  rho GTPase-activating protein 23 isoform X6

   See identical proteins and their annotated locations for XP_006722056.1

   Conserved Domains (4) summary

   cd00992
   Location:41 → 151

   PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

   cd04395
   Location:902 → 1097

   RhoGAP_ARHGAP21; RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the ...

   cd01253
   Location:690 → 810

   PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

   pfam00169
   Location:689 → 808

   PH; PH domain

3. XM_006721992.4 → XP_006722055.1  rho GTPase-activating protein 23 isoform X3

   See identical proteins and their annotated locations for XP_006722055.1

   UniProtKB/TrEMBL

   A0A2X0SFL7

   Conserved Domains (3) summary

   cd00992
   Location:41 → 151

   PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

   cd04395
   Location:819 → 1014

   RhoGAP_ARHGAP21; RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the ...

   cl17171
   Location:590 → 727

   PH-like; Pleckstrin homology-like domain

4. XM_011525076.3 → XP_011523378.1  rho GTPase-activating protein 23 isoform X7

   See identical proteins and their annotated locations for XP_011523378.1

   Related

   ENSP00000482992.1, ENST00000620417.4

   Conserved Domains (4) summary

   cd00992
   Location:41 → 151

   PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

   cd04395
   Location:902 → 1097

   RhoGAP_ARHGAP21; RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the ...

   cd01253
   Location:690 → 810

   PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

   pfam00169
   Location:689 → 808

   PH; PH domain

5. XM_011525077.3 → XP_011523379.1  rho GTPase-activating protein 23 isoform X8

   See identical proteins and their annotated locations for XP_011523379.1

   Conserved Domains (4) summary

   cd00992
   Location:41 → 151

   PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

   cd04395
   Location:902 → 1097

   RhoGAP_ARHGAP21; RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the ...

   cd01253
   Location:690 → 810

   PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

   pfam00169
   Location:689 → 808

   PH; PH domain

6. XM_047436477.1 → XP_047292433.1  rho GTPase-activating protein 23 isoform X9

7. XM_011525074.3 → XP_011523376.1  rho GTPase-activating protein 23 isoform X4

   See identical proteins and their annotated locations for XP_011523376.1

   UniProtKB/TrEMBL

   A0A2X0SFL7

   Related

   ENSP00000516485.1, ENST00000616767.2

   Conserved Domains (4) summary

   PHA03247
   Location:77 → 499

   PHA03247; large tegument protein UL36; Provisional

   cd00992
   Location:4 → 57

   PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

   cd04395
   Location:808 → 1003

   RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

   cd01253
   Location:596 → 716

   PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

8. XM_011525073.2 → XP_011523375.1  rho GTPase-activating protein 23 isoform X1

   See identical proteins and their annotated locations for XP_011523375.1

   UniProtKB/TrEMBL

   A0A2X0SFL7

   Conserved Domains (4) summary

   cd00992
   Location:26 → 136

   PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

   cd04395
   Location:887 → 1082

   RhoGAP_ARHGAP21; RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the ...

   cd01253
   Location:675 → 795

   PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

   pfam00169
   Location:674 → 793

   PH; PH domain

9. XM_011525075.3 → XP_011523377.1  rho GTPase-activating protein 23 isoform X5

   See identical proteins and their annotated locations for XP_011523377.1

   UniProtKB/TrEMBL

   A0A2X0SFL7

   Conserved Domains (3) summary

   cd04395
   Location:696 → 891

   RhoGAP_ARHGAP21; RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the ...

   cd01253
   Location:484 → 604

   PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

   pfam00169
   Location:483 → 602

   PH; PH domain

RNA

1. XR_429909.4 RNA Sequence

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

1. NT_187614.1 Reference GRCh38.p14 ALT_REF_LOCI_1

   Range

   2454590..2547687

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_054329303.1 → XP_054185278.1  rho GTPase-activating protein 23 isoform X2

   UniProtKB/TrEMBL

   A0A9L9PXQ2

2. XM_054329307.1 → XP_054185282.1  rho GTPase-activating protein 23 isoform X6

3. XM_054329304.1 → XP_054185279.1  rho GTPase-activating protein 23 isoform X3

4. XM_054329308.1 → XP_054185283.1  rho GTPase-activating protein 23 isoform X7

5. XM_054329310.1 → XP_054185285.1  rho GTPase-activating protein 23 isoform X9

6. XM_054329309.1 → XP_054185284.1  rho GTPase-activating protein 23 isoform X8

7. XM_054329305.1 → XP_054185280.1  rho GTPase-activating protein 23 isoform X4

8. XM_054329302.1 → XP_054185277.1  rho GTPase-activating protein 23 isoform X1

9. XM_054329306.1 → XP_054185281.1  rho GTPase-activating protein 23 isoform X5

RNA

1. XR_008485634.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

1. NC_060941.1 Alternate T2T-CHM13v2.0

   Range

   39282325..39375417

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_054316779.1 → XP_054172754.1  rho GTPase-activating protein 23 isoform X2

   UniProtKB/TrEMBL

   A0A9L9PXQ2

2. XM_054316783.1 → XP_054172758.1  rho GTPase-activating protein 23 isoform X6

3. XM_054316780.1 → XP_054172755.1  rho GTPase-activating protein 23 isoform X3

4. XM_054316784.1 → XP_054172759.1  rho GTPase-activating protein 23 isoform X7

5. XM_054316786.1 → XP_054172761.1  rho GTPase-activating protein 23 isoform X9

6. XM_054316785.1 → XP_054172760.1  rho GTPase-activating protein 23 isoform X8

7. XM_054316781.1 → XP_054172756.1  rho GTPase-activating protein 23 isoform X4

8. XM_054316778.1 → XP_054172753.1  rho GTPase-activating protein 23 isoform X1

9. XM_054316782.1 → XP_054172757.1  rho GTPase-activating protein 23 isoform X5

RNA

1. XR_008484866.1 RNA Sequence

The following Reference Sequences have been suppressed. Explain

These RefSeqs were suppressed for the cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links, or BLAST links (BLink), but may still be retrieved by clicking on their accession.version below.

1. NM_020876.1: Suppressed sequence

   Description

   NM_020876.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate, and the CDS is partial on the 5' end.