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Cts6 cathepsin 6 [ Mus musculus (house mouse) ]

Gene ID: 58518, updated on 23-Jun-2021

Summary

Official Symbol
Cts6provided by MGI
Official Full Name
cathepsin 6provided by MGI
Primary source
MGI:MGI:1889619
See related
Ensembl:ENSMUSG00000021441
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1600022N02Rik
Expression
Low expression observed in reference dataset See more
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Genomic context

See Cts6 in Genome Data Viewer
Location:
13 B2; 13 32.67 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (61342961..61351206, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (61195147..61203392, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (61296508..61304753, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 930 pseudogene Neighboring gene cathepsin R Neighboring gene cathepsin 8 Neighboring gene cathepsin 8, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Clone Names

  • MGC117650

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables collagen binding ISO
Inferred from Sequence Orthology
more info
 
enables cysteine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cysteine-type endopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
enables cysteine-type peptidase activity ISO
Inferred from Sequence Orthology
more info
 
enables fibronectin binding ISO
Inferred from Sequence Orthology
more info
 
enables histone binding ISO
Inferred from Sequence Orthology
more info
 
enables proteoglycan binding ISO
Inferred from Sequence Orthology
more info
 
enables serpin family protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in collagen catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in fusion of virus membrane with host endosome membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in fusion of virus membrane with host plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein autoprocessing ISO
Inferred from Sequence Orthology
more info
 
involved_in proteolysis ISO
Inferred from Sequence Orthology
more info
 
involved_in proteolysis involved in cellular protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in proteolysis involved in cellular protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in receptor-mediated endocytosis of virus by host cell ISO
Inferred from Sequence Orthology
more info
 
involved_in viral entry into host cell ISO
Inferred from Sequence Orthology
more info
 
involved_in zymogen activation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
 
located_in multivesicular body ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021445.1NP_067420.1  cathepsin 6 precursor

    See identical proteins and their annotated locations for NP_067420.1

    Status: PROVISIONAL

    Source sequence(s)
    AF223401
    Consensus CDS
    CCDS26586.1
    UniProtKB/TrEMBL
    Q9ET52
    Related
    ENSMUSP00000021890.5, ENSMUST00000021890.5
    Conserved Domains (3) summary
    PTZ00203
    Location:7332
    PTZ00203; cathepsin L protease; Provisional
    smart00848
    Location:2987
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    cd02248
    Location:116332
    Peptidase_C1A; Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences, ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    61342961..61351206 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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