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DMD dystrophin [ Canis lupus familiaris (dog) ]

Gene ID: 606758, updated on 4-Nov-2022

Summary

Official Symbol
DMDprovided by VGNC
Official Full Name
dystrophinprovided by VGNC
Primary source
VGNC:VGNC:54134
See related
Ensembl:ENSCAFG00845017750
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

See DMD in Genome Data Viewer
Location:
chromosome: X
Exon count:
86
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (26319830..28487633, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (31264482..33330008, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (26455978..28540050, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (26365124..28433100, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (26358103..28426635, complement)
105 previous assembly CanFam3.1 (GCF_000002285.3) X NC_006621.3 (26290903..28444635, complement)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene ferritin heavy chain-like Neighboring gene uncharacterized LOC111094663 Neighboring gene 40S ribosomal protein S15a-like Neighboring gene uncharacterized LOC119868427 Neighboring gene protein lin-28 homolog A-like Neighboring gene RNA polymerase II elongation factor ELL2-like Neighboring gene uncharacterized LOC111094964 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane bounded cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003343.1NP_001003343.1  dystrophin

    See identical proteins and their annotated locations for NP_001003343.1

    Status: PROVISIONAL

    Source sequence(s)
    AF070485
    UniProtKB/Swiss-Prot
    O97592
    Related
    ENSCAFP00845027617.1, ENSCAFT00845035278.1
    Conserved Domains (10) summary
    COG1340
    Location:17061976
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00014
    Location:16119
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:345559
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:30543083
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:33063354
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    pfam00435
    Location:29293035
    Spectrin; Spectrin repeat
    pfam09068
    Location:30843202
    EF-hand_2; EF hand
    pfam09069
    Location:32063297
    EF-hand_3; EF-hand
    pfam16769
    Location:34833666
    MCM3AP_GANP; MCM3AP domain of GANP
    cl02488
    Location:14691678
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    26319830..28487633 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038448876.1XP_038304804.1  dystrophin isoform X3

    Conserved Domains (9) summary
    cd00176
    Location:337551
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:30463075
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:32983346
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:11201930
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:31123273
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:29213027
    Spectrin; Spectrin repeat
    cd21231
    Location:3113
    CH_DMD_rpt1; first calponin homology (CH) domain found in dystrophin and similar proteins
    cd21233
    Location:128238
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:553820
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  2. XM_038448883.1XP_038304811.1  dystrophin isoform X10

    Conserved Domains (8) summary
    cd00176
    Location:222436
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:29302959
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:31823230
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:10051815
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:29963157
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:28052911
    Spectrin; Spectrin repeat
    cd21233
    Location:13123
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:438705
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  3. XM_038448880.1XP_038304808.1  dystrophin isoform X7

    Conserved Domains (9) summary
    cd00176
    Location:301515
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:30103039
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:32623310
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:10841894
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:30763237
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:28852991
    Spectrin; Spectrin repeat
    cd21231
    Location:11121
    CH_DMD_rpt1; first calponin homology (CH) domain found in dystrophin and similar proteins
    cd21233
    Location:136246
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:517784
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  4. XM_038448881.1XP_038304809.1  dystrophin isoform X8

    Conserved Domains (9) summary
    cd00176
    Location:345559
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:30083037
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:32603308
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:11281925
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:30743235
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:28832989
    Spectrin; Spectrin repeat
    cd21231
    Location:11121
    CH_DMD_rpt1; first calponin homology (CH) domain found in dystrophin and similar proteins
    cd21233
    Location:136246
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:561828
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  5. XM_038448875.1XP_038304803.1  dystrophin isoform X2

    Conserved Domains (9) summary
    cd00176
    Location:345559
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:30533082
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:33053353
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:11281938
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:31193280
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:29283034
    Spectrin; Spectrin repeat
    cd21231
    Location:11121
    CH_DMD_rpt1; first calponin homology (CH) domain found in dystrophin and similar proteins
    cd21233
    Location:136246
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:561828
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  6. XM_038448878.1XP_038304806.1  dystrophin isoform X5

    Conserved Domains (9) summary
    cd00176
    Location:345559
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:30533082
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:33053353
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:11281938
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:31193280
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:29283034
    Spectrin; Spectrin repeat
    cd21231
    Location:11121
    CH_DMD_rpt1; first calponin homology (CH) domain found in dystrophin and similar proteins
    cd21233
    Location:136246
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:561828
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  7. XM_038448877.1XP_038304805.1  dystrophin isoform X4

    Conserved Domains (9) summary
    cd00176
    Location:345559
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:30543083
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:33063354
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:11281938
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:31203281
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:29293035
    Spectrin; Spectrin repeat
    cd21231
    Location:11121
    CH_DMD_rpt1; first calponin homology (CH) domain found in dystrophin and similar proteins
    cd21233
    Location:136246
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:561828
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  8. XM_038448879.1XP_038304807.1  dystrophin isoform X6

    Conserved Domains (9) summary
    cd00176
    Location:345559
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:30543083
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:33063354
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:11281938
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:31203281
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:29293035
    Spectrin; Spectrin repeat
    cd21231
    Location:11121
    CH_DMD_rpt1; first calponin homology (CH) domain found in dystrophin and similar proteins
    cd21233
    Location:136246
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:561828
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  9. XM_038448874.1XP_038304802.1  dystrophin isoform X1

    Conserved Domains (9) summary
    cd00176
    Location:345559
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:30543083
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:33063354
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:11281938
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:31203281
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:29293035
    Spectrin; Spectrin repeat
    cd21231
    Location:11121
    CH_DMD_rpt1; first calponin homology (CH) domain found in dystrophin and similar proteins
    cd21233
    Location:136246
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:561828
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  10. XM_038448882.1XP_038304810.1  dystrophin isoform X9

    Conserved Domains (8) summary
    cd00176
    Location:222436
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:29312960
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:31833231
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:10051815
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:29973158
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:28062912
    Spectrin; Spectrin repeat
    cd21233
    Location:13123
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:438705
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  11. XM_038448884.1XP_038304812.1  dystrophin isoform X11

    Conserved Domains (8) summary
    cd00176
    Location:131345
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:28402869
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:30923140
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:9141724
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:29063067
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:27152821
    Spectrin; Spectrin repeat
    cl00030
    Location:232
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:347614
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  12. XM_038448885.1XP_038304813.1  dystrophin isoform X12

    Conserved Domains (8) summary
    cd00176
    Location:116330
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:28252854
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:30773125
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02168
    Location:8991709
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16246
    Location:28913052
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:27002806
    Spectrin; Spectrin repeat
    cl00030
    Location:117
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:332599
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  13. XM_038448887.1XP_038304815.1  dystrophin isoform X14

    UniProtKB/TrEMBL
    A0A8P0T489
    Related
    ENSCAFP00845026508.1, ENSCAFT00845033876.1
    Conserved Domains (6) summary
    COG1196
    Location:9751145
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00176
    Location:230473
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:599628
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:851899
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    cd16246
    Location:665826
    EFh_DMD; EF-hand-like motif found in dystrophin
    pfam00435
    Location:474580
    Spectrin; Spectrin repeat
  14. XM_038448889.1XP_038304817.1  dystrophin isoform X16

    Conserved Domains (3) summary
    COG1196
    Location:354524
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd02334
    Location:243291
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    cd16246
    Location:57218
    EFh_DMD; EF-hand-like motif found in dystrophin
  15. XM_038448891.1XP_038304819.1  dystrophin isoform X18

    Conserved Domains (3) summary
    COG1196
    Location:354524
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd02334
    Location:243291
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    cd16246
    Location:57218
    EFh_DMD; EF-hand-like motif found in dystrophin
  16. XM_038448888.1XP_038304816.1  dystrophin isoform X15

    Conserved Domains (3) summary
    COG1196
    Location:367537
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd02334
    Location:243291
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    cd16246
    Location:57218
    EFh_DMD; EF-hand-like motif found in dystrophin
  17. XM_038448890.1XP_038304818.1  dystrophin isoform X17

    UniProtKB/TrEMBL
    A0A8C0SQ31
    Conserved Domains (3) summary
    COG1196
    Location:367537
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd02334
    Location:243291
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    cd16246
    Location:57218
    EFh_DMD; EF-hand-like motif found in dystrophin
  18. XM_038448886.1XP_038304814.1  dystrophin isoform X13

    Conserved Domains (6) summary
    cd00176
    Location:345559
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    TIGR02168
    Location:11281938
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00435
    Location:29293023
    Spectrin; Spectrin repeat
    cd21231
    Location:11121
    CH_DMD_rpt1; first calponin homology (CH) domain found in dystrophin and similar proteins
    cd21233
    Location:136246
    CH_DMD_rpt2; second calponin homology (CH) domain found in dystrophin and similar proteins
    cl02488
    Location:561781
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    26365124..28433100 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    26358103..28426635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    26455978..28540050 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    31264482..33330008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)