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KHK ketohexokinase [ Bos taurus (cattle) ]

Gene ID: 614868, updated on 5-Mar-2024

Summary

Official Symbol
KHKprovided by VGNC
Official Full Name
ketohexokinaseprovided by VGNC
Primary source
VGNC:VGNC:30543
See related
Ensembl:ENSBTAG00000011325
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

Location:
chromosome: 11
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (72537265..72550453, complement)

Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene prolactin regulatory element binding Neighboring gene abhydrolase domain containing 1 Neighboring gene cell growth regulator with EF-hand domain 1 Neighboring gene elastin microfibril interfacer 1 Neighboring gene oligosaccharyltransferase complex subunit 4, non-catalytic Neighboring gene AGBL carboxypeptidase 5

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Pathways from PubChem

General protein information

Preferred Names
ketohexokinase
Names
ketohexokinase (fructokinase)
NP_001069819.1
XP_024854916.1
XP_024854917.1
XP_024854918.1
XP_024854920.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076351.1NP_001069819.1  ketohexokinase

    See identical proteins and their annotated locations for NP_001069819.1

    Status: PROVISIONAL

    Source sequence(s)
    BC122772
    UniProtKB/TrEMBL
    E1BQ33, Q0II75
    Conserved Domains (1) summary
    cd01939
    Location:5340
    Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    72537265..72550453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024999152.2XP_024854920.1  ketohexokinase isoform X4

    Conserved Domains (1) summary
    cd01939
    Location:5250
    Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...
  2. XM_024999150.2XP_024854918.1  ketohexokinase isoform X2

    Related
    ENSBTAP00000015052.7, ENSBTAT00000015052.7
    Conserved Domains (1) summary
    cd01939
    Location:5295
    Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...
  3. XM_024999149.2XP_024854917.1  ketohexokinase isoform X3

    UniProtKB/TrEMBL
    F1N4P4, Q5EA35
    Related
    ENSBTAP00000101836.1, ENSBTAT00000118245.1
    Conserved Domains (1) summary
    cd01939
    Location:5295
    Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...
  4. XM_024999148.2XP_024854916.1  ketohexokinase isoform X1

    Related
    ENSBTAP00000052833.4, ENSBTAT00000053651.4
    Conserved Domains (1) summary
    cd01939
    Location:12320
    Ketohexokinase; Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose. KHK can also phosphorylate several other furanose sugars. It is found in higher eukaryotes ...