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Zfp963 zinc finger protein 963 [ Mus musculus (house mouse) ]

Gene ID: 620419, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp963provided by MGI
Official Full Name
zinc finger protein 963provided by MGI
Primary source
MGI:MGI:4867078
See related
Ensembl:ENSMUSG00000092260 AllianceGenome:MGI:4867078
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZNF44 (zinc finger protein 44); ZNF442 (zinc finger protein 442); and ZNF563 (zinc finger protein 563). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E14 (RPKM 3.7), CNS E11.5 (RPKM 3.5) and 28 other tissues See more
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Genomic context

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See Zfp963 in Genome Data Viewer
Location:
8 B3.3; 8 33.88 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (70194289..70202612, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (69741639..69749962, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 869 Neighboring gene STARR-positive B cell enhancer ABC_E9117 Neighboring gene STARR-positive B cell enhancer ABC_E242 Neighboring gene predicted gene, 51532 Neighboring gene STARR-positive B cell enhancer ABC_E6642 Neighboring gene STARR-seq mESC enhancer starr_21745 Neighboring gene predicted gene, 19893 Neighboring gene zinc finger protein 866 Neighboring gene STARR-positive B cell enhancer ABC_E6643

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Potential readthrough

Included gene: Zfp866

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 669-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001200023.1 → NP_001186952.1  zinc finger protein 669-like

    Status: VALIDATED

    Source sequence(s)
    AC157564, AK162670
    Consensus CDS
    CCDS52566.1
    UniProtKB/TrEMBL
    D3Z2T8
    Related
    ENSMUSP00000119087.2, ENSMUST00000130458.8
    Conserved Domains (5) summary
    smart00349
    Location:4 → 44
    KRAB; krueppel associated box
    COG5048
    Location:185 → 383
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:298 → 318
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4 → 41
    KRAB; KRAB box
    pfam13465
    Location:338 → 363
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    70194289..70202612 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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