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Itih6 inter-alpha-trypsin inhibitor heavy chain family member 6 [ Mus musculus (house mouse) ]

Gene ID: 634882, updated on 5-Mar-2024

Summary

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Official Symbol
Itih6provided by MGI
Official Full Name
inter-alpha-trypsin inhibitor heavy chain family member 6provided by MGI
Primary source
MGI:MGI:2685232
See related
Ensembl:ENSMUSG00000087149 AllianceGenome:MGI:2685232
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm386; Itih5l; Itih5l-ps
Expression
Biased expression in limb E14.5 (RPKM 3.1) and CNS E14 (RPKM 0.3) See more
Orthologs
human all
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Genomic context

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Location:
X F3; X 68.46 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (149609892..149640732)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (150826917..150857407)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 18773 Neighboring gene predicted gene, 24907 Neighboring gene MAGE family member D2 Neighboring gene predicted gene, 54086 Neighboring gene STARR-seq mESC enhancer starr_48073 Neighboring gene polypyrimidine tract binding protein 1 pseudogene Neighboring gene guanine nucleotide binding protein nucleolar 3 like Neighboring gene STARR-positive B cell enhancer ABC_E8765

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
inter-alpha-trypsin inhibitor heavy chain H6
Names
inter-alpha (globulin) inhibitor H5-like, pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001289875.2 → NP_001276804.2  inter-alpha-trypsin inhibitor heavy chain H6 precursor

    Status: VALIDATED

    Source sequence(s)
    AL672282
    Related
    ENSMUST00000145639.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    149609892..149640732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017318592.3 → XP_017174081.1  inter-alpha-trypsin inhibitor heavy chain H6 isoform X1

    Conserved Domains (5) summary
    cd01461
    Location:291 → 475
    vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
    TIGR03788
    Location:62 → 641
    marine_srt_targ; marine proteobacterial sortase target protein
    pfam03154
    Location:633 → 1007
    Atrophin-1; Atrophin-1 family
    pfam06668
    Location:1100 → 1229
    ITI_HC_C; Inter-alpha-trypsin inhibitor heavy chain C-terminus
    cl02699
    Location:51 → 161
    VIT; Vault protein inter-alpha-trypsin domain

  2. XM_017318593.3 → XP_017174082.1  inter-alpha-trypsin inhibitor heavy chain H6 isoform X2

    Conserved Domains (4) summary
    cd01461
    Location:291 → 475
    vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
    TIGR03788
    Location:62 → 641
    marine_srt_targ; marine proteobacterial sortase target protein
    pfam03154
    Location:633 → 1007
    Atrophin-1; Atrophin-1 family
    cl02699
    Location:51 → 161
    VIT; Vault protein inter-alpha-trypsin domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_003597.1: Suppressed sequence

    Description
    NR_003597.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein
Heading Accession and Version

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