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Sv2b synaptic vesicle glycoprotein 2 b [ Mus musculus (house mouse) ]

Gene ID: 64176, updated on 23-Jun-2021

Summary

Official Symbol
Sv2bprovided by MGI
Official Full Name
synaptic vesicle glycoprotein 2 bprovided by MGI
Primary source
MGI:MGI:1927338
See related
Ensembl:ENSMUSG00000053025
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI850768; mKIAA0735; A830038F04Rik
Expression
Biased expression in cortex adult (RPKM 34.7), frontal lobe adult (RPKM 26.9) and 2 other tissues See more
Orthologs
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Genomic context

See Sv2b in Genome Data Viewer
Location:
7; 7 D1
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (74764642..74959143, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (75114894..75309262, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (82259780..82454148, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53361 Neighboring gene RIKEN cDNA 4930533N22 gene Neighboring gene RIKEN cDNA 1500012K07 gene Neighboring gene ribosomal protein S28 pseudogene Neighboring gene predicted gene, 46017

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC38746

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within chemical synaptic transmission TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within neurotransmitter transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of synaptic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in synaptic vesicle ISO
Inferred from Sequence Orthology
more info
 
is_active_in synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
synaptic vesicle glycoprotein 2B
Names
synaptic vesicle protein 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109753.1NP_001103223.1  synaptic vesicle glycoprotein 2B

    See identical proteins and their annotated locations for NP_001103223.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
    Source sequence(s)
    AK043830, AK147261, BC060224, BY269935
    Consensus CDS
    CCDS21368.1
    UniProtKB/Swiss-Prot
    Q8BG39
    Related
    ENSMUSP00000082254.6, ENSMUST00000085164.7
    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  2. NM_001360571.1NP_001347500.1  synaptic vesicle glycoprotein 2B

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript. All seven variants encode the same protein.
    Source sequence(s)
    AC113471, AC116898, AC127355
    Consensus CDS
    CCDS21368.1
    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  3. NM_001360572.1NP_001347501.1  synaptic vesicle glycoprotein 2B

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
    Source sequence(s)
    AC113471, AC116898, AC127355
    Consensus CDS
    CCDS21368.1
    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  4. NM_001360573.1NP_001347502.1  synaptic vesicle glycoprotein 2B

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
    Source sequence(s)
    AC113471, AC116898, AC127355
    Consensus CDS
    CCDS21368.1
    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  5. NM_001360574.1NP_001347503.1  synaptic vesicle glycoprotein 2B

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
    Source sequence(s)
    AC113471, AC116898, AC127355
    Consensus CDS
    CCDS21368.1
    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  6. NM_001360575.1NP_001347504.1  synaptic vesicle glycoprotein 2B

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
    Source sequence(s)
    AC116898, AK029736, BC060224
    Consensus CDS
    CCDS21368.1
    Related
    ENSMUSP00000146049.2, ENSMUST00000206344.2
    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  7. NM_153579.4NP_705807.2  synaptic vesicle glycoprotein 2B

    See identical proteins and their annotated locations for NP_705807.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. All seven variants encode the same protein.
    Source sequence(s)
    BC060224, BC079568
    Consensus CDS
    CCDS21368.1
    UniProtKB/Swiss-Prot
    Q8BG39
    Related
    ENSMUSP00000127245.2, ENSMUST00000165175.8
    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    74764642..74959143 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153323.1XP_036009216.1  synaptic vesicle glycoprotein 2B isoform X1

    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  2. XM_036153324.1XP_036009217.1  synaptic vesicle glycoprotein 2B isoform X1

    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  3. XM_006541059.4XP_006541122.1  synaptic vesicle glycoprotein 2B isoform X1

    See identical proteins and their annotated locations for XP_006541122.1

    UniProtKB/Swiss-Prot
    Q8BG39
    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
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