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IGBP1C IGBP1 family member C [ Homo sapiens (human) ]

Gene ID: 645545, updated on 5-Mar-2024

Summary

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Official Symbol
IGBP1Cprovided by HGNC
Official Full Name
IGBP1 family member Cprovided by HGNC
Primary source
HGNC:HGNC:43611
See related
Ensembl:ENSG00000266826 AllianceGenome:HGNC:43611
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IGBP1P2
Summary
Predicted to enable protein phosphatase 2A binding activity. Predicted to be involved in regulation of dephosphorylation. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
17q22
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (58660424..58692045, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (59528282..59559911, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (56737785..56769406, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene testis expressed 14, intercellular bridge forming factor Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:56709807-56710349 Neighboring gene uncharacterized LOC105371842 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:56712589-56713090 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:56713091-56713590 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr17:56735252-56735804 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr17:56735936-56736706 Neighboring gene U1 spliceosomal RNA Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:56738569-56739070 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12489 Neighboring gene RNA, U1 small nuclear 108, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12490 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12491 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:56777426-56777594 Neighboring gene RNA, U1 small nuclear 52, pseudogene Neighboring gene RNA, variant U1 small nuclear 34 Neighboring gene MPRA-validated peak2919 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12492 Neighboring gene uncharacterized LOC105371843 Neighboring gene RAD51 paralog C Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8775 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:56833223-56833371 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1E Neighboring gene RNA, U6 small nuclear 518, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The sequence of the human genome. Venter JC, et al. Science, 2001 Feb 16. PMID 11181995
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein phosphatase 2A binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
immunoglobulin-binding protein 1 family member C
Names
hCG1642624
immunoglobulin (CD79A) binding protein 1 family member C
immunoglobulin (CD79A) binding protein 1 pseudogene 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395966.1 → NP_001382895.1  immunoglobulin-binding protein 1 family member C

    Status: VALIDATED

    Source sequence(s)
    AC011195
    Consensus CDS
    CCDS92369.1
    UniProtKB/Swiss-Prot
    A0A1W2PR95
    Related
    ENSP00000492384.1, ENST00000583666.3
    Conserved Domains (1) summary
    pfam04177
    Location:14 → 329
    TAP42; TAP42-like family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    58660424..58692045 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    59528282..59559911 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_012738.2: Suppressed sequence

    Description
    NG_012738.2: This RefSeq was removed because it is now thought that this gene is a coding retrogene.

  2. NM_001101392.1: Suppressed sequence

    Description
    NM_001101392.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A1W2PR95.1 GenPept UniProtKB/Swiss-Prot:A0A1W2PR95

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.