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Bhmt2 betaine-homocysteine methyltransferase 2 [ Mus musculus (house mouse) ]

Gene ID: 64918, updated on 23-Jun-2021

Summary

Official Symbol
Bhmt2provided by MGI
Official Full Name
betaine-homocysteine methyltransferase 2provided by MGI
Primary source
MGI:MGI:1891379
See related
Ensembl:ENSMUSG00000042118
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C81077; D13Ucl; D13Ucla2
Expression
Biased expression in liver adult (RPKM 63.9), liver E18 (RPKM 58.7) and 4 other tissues See more
Orthologs
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Genomic context

See Bhmt2 in Genome Data Viewer
Location:
13 C3; 13 47.88 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (93792605..93810810, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (93656097..93674302, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (94426052..94444257, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31977 Neighboring gene betaine-homocysteine methyltransferase Neighboring gene dimethylglycine dehydrogenase precursor Neighboring gene expressed sequence AW495222 Neighboring gene predicted gene, 41021

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables S-adenosylmethionine-homocysteine S-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables S-methylmethionine-homocysteine S-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables S-methylmethionine-homocysteine S-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables betaine-homocysteine S-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in L-methionine salvage ISO
Inferred from Sequence Orthology
more info
 
involved_in S-adenosylmethionine metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in S-methylmethionine metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within methionine biosynthetic process ISO
Inferred from Sequence Orthology
more info
PubMed 
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
S-methylmethionine--homocysteine S-methyltransferase BHMT2
Names
SMM-hcy methyltransferase
betaine--homocysteine S-methyltransferase 2
NP_075022.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022884.2NP_075022.2  S-methylmethionine--homocysteine S-methyltransferase BHMT2

    See identical proteins and their annotated locations for NP_075022.2

    Status: VALIDATED

    Source sequence(s)
    AA014354, AK145901
    Consensus CDS
    CCDS26689.1
    UniProtKB/Swiss-Prot
    Q91WS4
    Related
    ENSMUSP00000015941.8, ENSMUST00000015941.8
    Conserved Domains (1) summary
    pfam02574
    Location:23305
    S-methyl_trans; Homocysteine S-methyltransferase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    93792605..93810810 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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