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HNRNPCL3 heterogeneous nuclear ribonucleoprotein C like 3 [ Homo sapiens (human) ]

Gene ID: 649330, updated on 3-Mar-2024

Summary

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Official Symbol
HNRNPCL3provided by HGNC
Official Full Name
heterogeneous nuclear ribonucleoprotein C like 3provided by HGNC
Primary source
HGNC:HGNC:51235
See related
Ensembl:ENSG00000277058 AllianceGenome:HGNC:51235
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HNRNPCL2; HNRNPCL4
Summary
Predicted to enable RNA binding activity. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
1p36.21
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (13060769..13062878)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene PRAME family member 28, pseudogene Neighboring gene PRAME family member 27 Neighboring gene PRAME family member 25 Neighboring gene PRAME family member 34, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. Cloutier P, et al. PLoS Genet, 2013. PMID 23349634, Free PMC Article
  2. MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation. Seo G, et al. Cell Rep, 2020 Jul 7. PMID 32640226, Free PMC Article
  3. STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production. Li D, et al. Cell Rep, 2019 Oct 29. PMID 31665637
  4. Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15. Han T, et al. Science, 2017 Apr 28. PMID 28302793
  5. Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair. Lu H, et al. Nat Commun, 2017 Dec 11. PMID 29229926, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
heterogeneous nuclear ribonucleoprotein C-like 3
Names
Heterogeneous nuclear ribonucleoprotein C-like 4
heterogeneous nuclear ribonucleoprotein C-like 2
hnRNP C-like-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001382358.1 → NP_001369287.1  heterogeneous nuclear ribonucleoprotein C-like 3

    Status: VALIDATED

    Source sequence(s)
    AC245056
    Consensus CDS
    CCDS72705.1
    UniProtKB/Swiss-Prot
    B7ZW38, P0DMR1
    UniProtKB/TrEMBL
    A0A0G2JPF8
    Related
    ENSP00000478017.1, ENST00000617807.3
    Conserved Domains (1) summary
    cl17169
    Location:10 → 93
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    13060769..13062878
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_012132914.1 Reference GRCh38.p14 PATCHES

    Range
    215109..217218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_015495298.1 Reference GRCh38.p14 PATCHES

    Range
    56385..58494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001146181.4: Suppressed sequence

    Description
    NM_001146181.4: This RefSeq was removed because currently there is insufficient support for the transcript.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7ZW38.1 GenPept UniProtKB/Swiss-Prot:B7ZW38

Gene LinkOut

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