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Rps8 ribosomal protein S8 [ Rattus norvegicus (Norway rat) ]

Gene ID: 65136, updated on 11-Apr-2024

Summary

Official Symbol
Rps8provided by RGD
Official Full Name
ribosomal protein S8provided by RGD
Primary source
RGD:61910
See related
Ensembl:ENSRNOG00000054626 AllianceGenome:RGD:61910
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Orthologous to human RPS8 (ribosomal protein S8). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 3609.3), Thymus (RPKM 3037.8) and 9 other tissues See more
Orthologs
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Genomic context

Location:
5q36
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (135866941..135869511, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (130630362..130632932, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (136020941..136023511, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene dynein light chain Tctex-type 4 Neighboring gene polo-like kinase 3 Neighboring gene bestrophin 4 Neighboring gene small nucleolar RNA, C/D box 38B Neighboring gene small nucleolar RNA, C/D box 38A Neighboring gene small nucleolar RNA, C/D box 46 Neighboring gene small nucleolar RNA, C/D box 55 Neighboring gene kinesin family member 2C Neighboring gene transfer RNA alanine (anticodon AGC) 53

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
PubMed 
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
 
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
small ribosomal subunit protein eS8
Names
40S ribosomal protein S8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031706.1NP_113894.1  small ribosomal subunit protein eS8

    See identical proteins and their annotated locations for NP_113894.1

    Status: PROVISIONAL

    Source sequence(s)
    X06423
    UniProtKB/Swiss-Prot
    P62243
    UniProtKB/TrEMBL
    A0A8L2R9H0, B2RYR8
    Related
    ENSRNOP00000074753.2, ENSRNOT00000081747.2
    Conserved Domains (1) summary
    PTZ00148
    Location:1206
    PTZ00148; 40S ribosomal protein S8; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    135866941..135869511 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063288367.1XP_063144437.1  small ribosomal subunit protein eS8 isoform X1