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Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a [ Mus musculus (house mouse) ]

Gene ID: 66222, updated on 9-May-2021

Summary

Official Symbol
Serpinb1aprovided by MGI
Official Full Name
serine (or cysteine) peptidase inhibitor, clade B, member 1aprovided by MGI
Primary source
MGI:MGI:1913472
See related
Ensembl:ENSMUSG00000044734
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
E; L; EI; MN; EIA; ELA; LEI; M/N; PI2; ova; MNEI; M/NEI; ELANH2; AI325983; 1190005M04Rik
Expression
Biased expression in large intestine adult (RPKM 90.3), duodenum adult (RPKM 21.7) and 10 other tissues See more
Orthologs
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Genomic context

See Serpinb1a in Genome Data Viewer
Location:
13 A3.2; 13 13.75 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (33026075..33037189, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (32842092..32853206, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (32933961..32943054, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene myosin light chain kinase family, member 4 Neighboring gene Werner helicase interacting protein 1 Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Neighboring gene predicted gene, 35899

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC129309

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables peptidase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
contributes_to serine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic ribonucleoprotein granule ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular region ISO
Inferred from Sequence Orthology
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
leukocyte elastase inhibitor A
Names
ovalbumin
serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1a
serine (or cysteine) proteinase inhibitor, clade B, member 1a
serine protease inhibitor EIA
serpin B1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025429.2NP_079705.2  leukocyte elastase inhibitor A

    See identical proteins and their annotated locations for NP_079705.2

    Status: VALIDATED

    Source sequence(s)
    AI325983, AK160167, BY266933
    Consensus CDS
    CCDS26428.1
    UniProtKB/Swiss-Prot
    Q9D154
    Related
    ENSMUSP00000075690.7, ENSMUST00000076352.8
    Conserved Domains (1) summary
    cd19560
    Location:1379
    serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    33026075..33037189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030247348.2XP_030103208.1  leukocyte elastase inhibitor A isoform X1

    Conserved Domains (1) summary
    cd19560
    Location:1379
    serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)
  2. XM_006516724.3XP_006516787.1  leukocyte elastase inhibitor A isoform X1

    See identical proteins and their annotated locations for XP_006516787.1

    UniProtKB/Swiss-Prot
    Q9D154
    Conserved Domains (1) summary
    cd19560
    Location:1379
    serpinB1_LEI; serpin family B member 1 (serpin B1), leukocyte elastase inhibitor (LEI)
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