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Sec11c SEC11 homolog C, signal peptidase complex subunit [ Mus musculus (house mouse) ]

Gene ID: 66286, updated on 23-Jun-2021

Summary

Official Symbol
Sec11cprovided by MGI
Official Full Name
SEC11 homolog C, signal peptidase complex subunitprovided by MGI
Primary source
MGI:MGI:1913536
See related
Ensembl:ENSMUSG00000024516
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sec11; Sec11l3; 1810029G24Rik
Expression
Ubiquitous expression in genital fat pad adult (RPKM 32.7), cerebellum adult (RPKM 26.8) and 28 other tissues See more
Orthologs
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Genomic context

See Sec11c in Genome Data Viewer
Location:
18; 18 E1
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (65933649..65950731)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (65800578..65817660)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (65960232..65977311)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene O-acyltransferase like Neighboring gene uncharacterized LOC118568361 Neighboring gene predicted gene, 52375 Neighboring gene predicted gene, 30094 Neighboring gene gastrin releasing peptide

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
 
involved_in signal peptide processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
part_of signal peptidase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
signal peptidase complex catalytic subunit SEC11C
Names
SEC11-like protein 3
SPC21
SPase 21 kDa subunit
Sec11-like 3
microsomal signal peptidase 21 kDa subunit
NP_079744.1
XP_006526213.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025468.2NP_079744.1  signal peptidase complex catalytic subunit SEC11C

    See identical proteins and their annotated locations for NP_079744.1

    Status: PROVISIONAL

    Source sequence(s)
    AK007641
    Consensus CDS
    CCDS29309.1
    UniProtKB/Swiss-Prot
    Q9D8V7
    Related
    ENSMUSP00000025394.7, ENSMUST00000025394.14
    Conserved Domains (1) summary
    cl10465
    Location:34167
    Peptidase_S24_S26; The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    65933649..65950731
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006526150.3XP_006526213.1  signal peptidase complex catalytic subunit SEC11C isoform X1

    See identical proteins and their annotated locations for XP_006526213.1

    Conserved Domains (1) summary
    cl10465
    Location:12129
    Peptidase_S24_S26; The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the ...
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