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Snhg16 small nucleolar RNA host gene 16 [ Mus musculus (house mouse) ]

Gene ID: 66293, updated on 8-Feb-2024

Summary

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Official Symbol
Snhg16provided by MGI
Official Full Name
small nucleolar RNA host gene 16provided by MGI
Primary source
MGI:MGI:1913543
See related
Ensembl:ENSMUSG00000020812 AllianceGenome:MGI:1913543
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810032O08Rik
Summary
Orthologous to human SNHG16 (small nucleolar RNA host gene 16). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 8.6), CNS E11.5 (RPKM 7.0) and 28 other tissues See more
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Genomic context

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See Snhg16 in Genome Data Viewer
Location:
11 E2; 11 81.49 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (116562486..116566624)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (116671660..116675798)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene arylalkylamine N-acetyltransferase Neighboring gene rhomboid 5 homolog 2 Neighboring gene STARR-seq mESC enhancer starr_31215 Neighboring gene STARR-seq mESC enhancer starr_31216 Neighboring gene cytoglobin Neighboring gene photoreceptor disc component Neighboring gene STARR-positive B cell enhancer ABC_E471 Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Neighboring gene small nucleolar RNA, C/D box 1C Neighboring gene small nucleolar RNA, C/D box 1B Neighboring gene small nucleolar RNA, C/D box 1A Neighboring gene STARR-seq mESC enhancer starr_31219 Neighboring gene STARR-seq mESC enhancer starr_31222 Neighboring gene predicted gene 11735

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. LncRNA SNHG16 induces proliferation and fibrogenesis via modulating miR-141-3p and CCND1 in diabetic nephropathy. Jiang X, et al. Gene Ther, 2020 Dec. PMID 32504027
  2. LncRNA SNHG16 promotes pulmonary fibrosis by targeting miR-455-3p to regulate the Notch2 pathway. Liu P, et al. Respir Res, 2021 Feb 6. PMID 33549106, Free PMC Article
  3. LncRNA SNHG16 regulates RAS and NF-κB pathway-mediated NLRP3 inflammasome activation to aggravate diabetes nephropathy through stabilizing TLR4. Liu Y, et al. Acta Diabetol, 2023 Apr. PMID 36658449
  4. UPF2 is a critical regulator of liver development, function and regeneration. Thoren LA, et al. PLoS One, 2010 Jul 19. PMID 20657840, Free PMC Article
  5. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SNHG16/miR-205/HDAC5 is involved in the progression of renal fibrosis.
    Title: SNHG16/miR-205/HDAC5 is involved in the progression of renal fibrosis.
  2. Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus.
    Title: Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus.
  3. LncRNA SNHG16 regulates RAS and NF-kappaB pathway-mediated NLRP3 inflammasome activation to aggravate diabetes nephropathy through stabilizing TLR4.
    Title: LncRNA SNHG16 regulates RAS and NF-κB pathway-mediated NLRP3 inflammasome activation to aggravate diabetes nephropathy through stabilizing TLR4.
  4. LncRNA SNHG16 promotes pulmonary fibrosis by targeting miR-455-3p to regulate the Notch2 pathway.
    Title: LncRNA SNHG16 promotes pulmonary fibrosis by targeting miR-455-3p to regulate the Notch2 pathway.
  5. LncRNA SNHG16 induces proliferation and fibrogenesis via modulating miR-141-3p and CCND1 in diabetic nephropathy.
    Title: LncRNA SNHG16 induces proliferation and fibrogenesis via modulating miR-141-3p and CCND1 in diabetic nephropathy.
Submit: New GeneRIF Correction

General gene information

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Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_027819.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the most predominant transcript.
    Source sequence(s)
    AK007675, BC055707
    Related
    ENSMUST00000139934.9

  2. NR_027820.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) is missing an internal exon at the 5' end compared to variant 1.
    Source sequence(s)
    AK007675, AK013681, BC055707
    Related
    ENSMUST00000142834.9

  3. NR_027821.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an additional segment at the 3' end compared to variant 1.
    Source sequence(s)
    AK007675, BC055707
    Related
    ENSMUST00000106378.9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    116562486..116566624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_025472.2: Suppressed sequence

    Description
    NM_025472.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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