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Rmdn1 regulator of microtubule dynamics 1 [ Mus musculus (house mouse) ]

Gene ID: 66302, updated on 11-Apr-2024

Summary

Official Symbol
Rmdn1provided by MGI
Official Full Name
regulator of microtubule dynamics 1provided by MGI
Primary source
MGI:MGI:1913552
See related
Ensembl:ENSMUSG00000028229 AllianceGenome:MGI:1913552
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RMD-1; Fam82b
Summary
Predicted to enable microtubule binding activity. Located in mitochondrion. Orthologous to human RMDN1 (regulator of microtubule dynamics 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 3.5), CNS E18 (RPKM 2.9) and 28 other tissues See more
Orthologs
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Genomic context

Location:
4 A3; 4 7.56 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (19575036..19606932)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (19575035..19606932)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene cyclic nucleotide gated channel beta 3 Neighboring gene SET pseudogene Neighboring gene STARR-seq mESC enhancer starr_09695 Neighboring gene STARR-seq mESC enhancer starr_09696 Neighboring gene copine III Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:19502117-19502304 Neighboring gene predicted gene, 52724 Neighboring gene WW domain containing E3 ubiquitin protein ligase 1 Neighboring gene predicted gene 12353 Neighboring gene STARR-positive B cell enhancer ABC_E9583 Neighboring gene STARR-positive B cell enhancer ABC_E2687 Neighboring gene predicted gene 12354

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in mitotic spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitotic spindle pole ISO
Inferred from Sequence Orthology
more info
 
is_active_in spindle microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in spindle microtubule ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
regulator of microtubule dynamics protein 1
Names
family with sequence similarity 82, member B
microtubule-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025476.6NP_079752.3  regulator of microtubule dynamics protein 1

    See identical proteins and their annotated locations for NP_079752.3

    Status: VALIDATED

    Source sequence(s)
    AK029446, AL683894, BY275756
    Consensus CDS
    CCDS17992.1
    UniProtKB/Swiss-Prot
    A2AGJ3, A9UN01, Q8C0Y9, Q8R166, Q9CWS6, Q9DCV4
    Related
    ENSMUSP00000029888.4, ENSMUST00000029888.4
    Conserved Domains (1) summary
    sd00006
    Location:199249
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    19575036..19606932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001784180.3 RNA Sequence

  2. XR_004941945.1 RNA Sequence