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Dpy30 dpy-30, histone methyltransferase complex regulatory subunit [ Mus musculus (house mouse) ]

Gene ID: 66310, updated on 23-Jun-2021

Summary

Official Symbol
Dpy30provided by MGI
Official Full Name
dpy-30, histone methyltransferase complex regulatory subunitprovided by MGI
Primary source
MGI:MGI:1913560
See related
Ensembl:ENSMUSG00000024067
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C87842; 2810410M20Rik
Expression
Ubiquitous expression in liver E14 (RPKM 36.7), testis adult (RPKM 34.1) and 28 other tissues See more
Orthologs
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Genomic context

See Dpy30 in Genome Data Viewer
Location:
17; 17 E2
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (74606469..74630939, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (74299474..74323944, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (74698814..74723284, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene mediator of cell motility 1 Neighboring gene F-box protein 34 pseudogene Neighboring gene predicted gene, 52299 Neighboring gene predicted gene, 31328 Neighboring gene predicted gene 9349

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
 
involved_in chromatin silencing at telomere IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in endosomal transport ISO
Inferred from Sequence Orthology
more info
 
involved_in histone H3-K4 methylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in histone H3-K4 methylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
part_of MLL3/4 complex ISO
Inferred from Sequence Orthology
more info
 
part_of Set1C/COMPASS complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of Set1C/COMPASS complex ISO
Inferred from Sequence Orthology
more info
 
part_of histone methyltransferase complex ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein dpy-30 homolog
Names
dosage compensation-related protein DPY30
dpy-30 homolog
dpy-30-like protein
dpy-30L

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001146222.1NP_001139694.1  protein dpy-30 homolog

    See identical proteins and their annotated locations for NP_001139694.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same protein.
    Source sequence(s)
    AK013073, BX518196
    Consensus CDS
    CCDS28970.1
    UniProtKB/Swiss-Prot
    Q99LT0
    Related
    ENSMUSP00000108190.4, ENSMUST00000112571.5
    Conserved Domains (1) summary
    pfam05186
    Location:5293
    Dpy-30; Dpy-30 motif
  2. NM_001146223.1NP_001139695.1  protein dpy-30 homolog

    See identical proteins and their annotated locations for NP_001139695.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same protein.
    Source sequence(s)
    AK013073, AK077902, AV460563
    Consensus CDS
    CCDS28970.1
    UniProtKB/Swiss-Prot
    Q99LT0
    Related
    ENSMUSP00000156795.2, ENSMUST00000233581.2
    Conserved Domains (1) summary
    pfam05186
    Location:5293
    Dpy-30; Dpy-30 motif
  3. NM_001146224.1NP_001139696.1  protein dpy-30 homolog

    See identical proteins and their annotated locations for NP_001139696.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-4 encode the same protein.
    Source sequence(s)
    AK003688, AK013073, BY123406
    Consensus CDS
    CCDS28970.1
    UniProtKB/Swiss-Prot
    Q99LT0
    Related
    ENSMUSP00000156830.2, ENSMUST00000232687.2
    Conserved Domains (1) summary
    pfam05186
    Location:5293
    Dpy-30; Dpy-30 motif
  4. NM_024428.4NP_077746.3  protein dpy-30 homolog

    See identical proteins and their annotated locations for NP_077746.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1-4 encode the same protein.
    Source sequence(s)
    AK013073, BU961422
    Consensus CDS
    CCDS28970.1
    UniProtKB/Swiss-Prot
    Q99LT0
    Related
    ENSMUSP00000126702.2, ENSMUST00000164832.9
    Conserved Domains (1) summary
    pfam05186
    Location:5293
    Dpy-30; Dpy-30 motif

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    74606469..74630939 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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