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Dctpp1 dCTP pyrophosphatase 1 [ Mus musculus (house mouse) ]

Gene ID: 66422, updated on 23-Jun-2021

Summary

Official Symbol
Dctpp1provided by MGI
Official Full Name
dCTP pyrophosphatase 1provided by MGI
Primary source
MGI:MGI:1913672
See related
Ensembl:ENSMUSG00000042462
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RS21-; RS21-C6; AI854235; 2410015N17Rik
Expression
Ubiquitous expression in CNS E11.5 (RPKM 40.4), liver E14.5 (RPKM 38.6) and 28 other tissues See more
Orthologs
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Genomic context

See Dctpp1 in Genome Data Viewer
Location:
7; 7 F3
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126856131..126859839, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127256959..127260667, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (134400473..134404181, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 4532 Neighboring gene zinc finger protein 553 Neighboring gene zinc finger protein 771 Neighboring gene selenophosphate synthetase 2 Neighboring gene ribosomal protein, large, P1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables dCTP diphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables dCTP diphosphatase activity ISO
Inferred from Sequence Orthology
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleoside-triphosphate diphosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables nucleoside-triphosphate diphosphatase activity ISO
Inferred from Sequence Orthology
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables pyrimidine deoxyribonucleotide binding IDA
Inferred from Direct Assay
more info
PubMed 
enables pyrophosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA protection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in DNA protection ISO
Inferred from Sequence Orthology
more info
 
involved_in dCTP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in dCTP catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in nucleoside triphosphate catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in nucleoside triphosphate catabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
NOT located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
NOT located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
dCTP pyrophosphatase 1
Names
XTP3-transactivated gene A protein homolog
dCTPase 1
deoxycytidine-triphosphatase 1
NP_075692.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023203.1NP_075692.1  dCTP pyrophosphatase 1

    See identical proteins and their annotated locations for NP_075692.1

    Status: PROVISIONAL

    Source sequence(s)
    AF110764
    Consensus CDS
    CCDS21862.1
    UniProtKB/Swiss-Prot
    Q9QY93
    Related
    ENSMUSP00000047845.5, ENSMUST00000035276.5
    Conserved Domains (1) summary
    cd11537
    Location:35125
    NTP-PPase_RS21-C6_like; Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    126856131..126859839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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