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Rdm1 RAD52 motif 1 [ Mus musculus (house mouse) ]

Gene ID: 66599, updated on 5-Mar-2024

Summary

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Official Symbol
Rdm1provided by MGI
Official Full Name
RAD52 motif 1provided by MGI
Primary source
MGI:MGI:1913849
See related
Ensembl:ENSMUSG00000010362 AllianceGenome:MGI:1913849
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rad52b; 2410008M22Rik
Summary
Predicted to enable DNA binding activity and RNA binding activity. Predicted to be located in cytosol. Predicted to be active in nucleolus. Is expressed in brain; central nervous system ganglion; sensory organ; and testis. Orthologous to human RDM1 (RAD52 motif containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 7.7), thymus adult (RPKM 7.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 D; 11 65.48 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (101517992..101526926)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (101627242..101636089)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_30771 Neighboring gene predicted gene, 26316 Neighboring gene STARR-seq mESC enhancer starr_30772 Neighboring gene uncharacterized LOC666331 Neighboring gene STARR-seq mESC enhancer starr_30774 Neighboring gene STARR-seq mESC enhancer starr_30775 Neighboring gene STARR-positive B cell enhancer ABC_E4003 Neighboring gene predicted gene, 23849 Neighboring gene STARR-seq mESC enhancer starr_30777 Neighboring gene predicted gene, 24950 Neighboring gene STARR-positive B cell enhancer ABC_E3024 Neighboring gene predicted gene, 23971

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. RDM1, a novel RNA recognition motif (RRM)-containing protein involved in the cell response to cisplatin in vertebrates. Hamimes S, et al. J Biol Chem, 2005 Mar 11. PMID 15611051
  2. siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors. Böhringer M, et al. Oncogene, 2013 Nov 28. PMID 23435420, Free PMC Article
  3. Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line. Cheverud JM, et al. Heredity (Edinb), 2014 May. PMID 24569637, Free PMC Article
  4. Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. Liu X, et al. BMC Immunol, 2016 Aug 2. PMID 27480124, Free PMC Article
  5. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. McKee AE, et al. BMC Dev Biol, 2005 Jul 20. PMID 16033648, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RAD52 motif-containing protein 1
Names
RAD52 homolog B
RAD52B homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025654.3 → NP_079930.1  RAD52 motif-containing protein 1

    See identical proteins and their annotated locations for NP_079930.1

    Status: VALIDATED

    Source sequence(s)
    AL590994
    Consensus CDS
    CCDS25477.1
    UniProtKB/Swiss-Prot
    Q9CQK3
    Related
    ENSMUSP00000010506.4, ENSMUST00000010506.10
    Conserved Domains (1) summary
    cd12364
    Location:15 → 95
    RRM_RDM1; RNA recognition motif of RAD52 motif-containing protein 1 (RDM1) and similar proteins

RNA

  1. NR_184640.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL590994

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    101517992..101526926
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006533945.4 → XP_006534008.1  RAD52 motif-containing protein 1 isoform X1

    Conserved Domains (1) summary
    cd12364
    Location:14 → 76
    RRM_RDM1; RNA recognition motif of RAD52 motif-containing protein 1 (RDM1) and similar proteins

  2. XM_011249178.4 → XP_011247480.1  RAD52 motif-containing protein 1 isoform X2

    Conserved Domains (1) summary
    cd12364
    Location:15 → 95
    RRM_RDM1; RNA recognition motif of RAD52 motif-containing protein 1 (RDM1) and similar proteins

RNA

  1. XR_003949490.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CQK3.1 GenPept UniProtKB/Swiss-Prot:Q9CQK3

Gene LinkOut

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