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Dcbld1 discoidin, CUB and LCCL domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 66686, updated on 23-Jun-2021

Summary

Official Symbol
Dcbld1provided by MGI
Official Full Name
discoidin, CUB and LCCL domain containing 1provided by MGI
Primary source
MGI:MGI:1913936
See related
Ensembl:ENSMUSG00000019891
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4631413K11Rik
Expression
Ubiquitous expression in duodenum adult (RPKM 9.1), large intestine adult (RPKM 8.4) and 27 other tissues See more
Orthologs
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Genomic context

See Dcbld1 in Genome Data Viewer
Location:
10; 10 B3
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (52109674..52197474)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (52233578..52321378)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (51953425..52041183)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene Ros1 proto-oncogene Neighboring gene predicted gene 20630 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene Ewing sarcoma breakpoint region 1 pseudogene Neighboring gene golgi associated PDZ and coiled-coil motif containing Neighboring gene ribosomal protein S19, pseudogene 10

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in zymogen activation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in blood microparticle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
discoidin, CUB and LCCL domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347444.1NP_001334373.1  discoidin, CUB and LCCL domain-containing protein 1 isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) has the same N- and C-termini, but is shorter than isoform 1.
    Source sequence(s)
    AC153525, AK014521, AK016485, AV229589, BY096153
    Consensus CDS
    CCDS83696.1
    UniProtKB/Swiss-Prot
    Q9D4J3
    Related
    ENSMUSP00000151265.2, ENSMUST00000218582.2
  2. NM_025705.4NP_079981.2  discoidin, CUB and LCCL domain-containing protein 1 isoform 1 precursor

    See identical proteins and their annotated locations for NP_079981.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC153525, AK014521, AK016485, AV229589, BY096153
    Consensus CDS
    CCDS23839.1
    UniProtKB/Swiss-Prot
    Q9D4J3
    Related
    ENSMUSP00000068203.6, ENSMUST00000069004.14
    Conserved Domains (2) summary
    cd00041
    Location:32140
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cl02694
    Location:147239
    LCCL; LCCL domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    52109674..52197474
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011243196.2XP_011241498.1  discoidin, CUB and LCCL domain-containing protein 1 isoform X1

    Conserved Domains (2) summary
    cd00041
    Location:32140
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cl02694
    Location:165229
    LCCL; LCCL domain
  2. XM_030245220.1XP_030101080.1  discoidin, CUB and LCCL domain-containing protein 1 isoform X2

  3. XM_030245221.2XP_030101081.1  discoidin, CUB and LCCL domain-containing protein 1 isoform X2

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