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Tmem186 transmembrane protein 186 [ Mus musculus (house mouse) ]

Gene ID: 66690, updated on 5-Mar-2024

Summary

Official Symbol
Tmem186provided by MGI
Official Full Name
transmembrane protein 186provided by MGI
Primary source
MGI:MGI:1913940
See related
Ensembl:ENSMUSG00000043140 AllianceGenome:MGI:1913940
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810440M13Rik; 4432406C05Rik
Summary
Located in mitochondrion. Orthologous to human TMEM186 (transmembrane protein 186). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 9.9), adrenal adult (RPKM 8.7) and 28 other tissues See more
Orthologs
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Genomic context

See Tmem186 in Genome Data Viewer
Location:
16 A1; 16 4.24 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (8451595..8455575, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (8633731..8637711, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene 4-aminobutyrate aminotransferase Neighboring gene zinc finger, MYND domain containing 19 pseudogene Neighboring gene ferritin light chain 2 pseudogene Neighboring gene phosphomannomutase 2 Neighboring gene STARR-positive B cell enhancer ABC_E8616 Neighboring gene calcium regulated heat stable protein 1 Neighboring gene LITAF domain containing Neighboring gene ubiquitin specific peptidase 7 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:8745912-8746157

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex I assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001362486.1NP_001349415.1  transmembrane protein 186 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC115005
  2. NM_025708.5NP_079984.2  transmembrane protein 186 isoform 1

    See identical proteins and their annotated locations for NP_079984.2

    Status: VALIDATED

    Source sequence(s)
    AC115005
    Consensus CDS
    CCDS27940.1
    UniProtKB/Swiss-Prot
    Q8BHA7, Q8BHT1, Q9CR76
    UniProtKB/TrEMBL
    Q78HW2
    Related
    ENSMUSP00000053862.9, ENSMUST00000052505.10

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    8451595..8455575 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)