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Spryd4 SPRY domain containing 4 [ Mus musculus (house mouse) ]

Gene ID: 66701, updated on 5-Mar-2024

Summary

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Official Symbol
Spryd4provided by MGI
Official Full Name
SPRY domain containing 4provided by MGI
Primary source
MGI:MGI:1913951
See related
Ensembl:ENSMUSG00000051346 AllianceGenome:MGI:1913951
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4633402N23Rik
Summary
Located in mitochondrion. Is expressed in genitourinary system. Orthologous to human SPRYD4 (SPRY domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E18 (RPKM 18.9), liver adult (RPKM 13.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10 D3; 10 76.44 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (128045777..128047663, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (128209908..128211794, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RNA binding motif, single stranded interacting protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E11466 Neighboring gene STARR-seq mESC enhancer starr_28269 Neighboring gene STARR-positive B cell enhancer ABC_E11760 Neighboring gene predicted gene 4556 Neighboring gene glutaminase 2 (liver, mitochondrial) Neighboring gene STARR-positive B cell enhancer ABC_E725 Neighboring gene STARR-positive B cell enhancer ABC_E10659 Neighboring gene timeless circadian clock 1 Neighboring gene predicted gene, 26847 Neighboring gene major intrinsic protein of lens fiber Neighboring gene STARR-seq mESC enhancer starr_28273

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  3. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
SPRY domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025716.2 → NP_079992.1  SPRY domain-containing protein 4

    See identical proteins and their annotated locations for NP_079992.1

    Status: PROVISIONAL

    Source sequence(s)
    AC135859
    Consensus CDS
    CCDS24264.1
    UniProtKB/Swiss-Prot
    Q8BUS6, Q91WK1, Q9D651
    Related
    ENSMUSP00000054731.9, ENSMUST00000061995.10
    Conserved Domains (1) summary
    cl02614
    Location:32 → 200
    SPRY; SPRY domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    128045777..128047663 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q91WK1.1 GenPept UniProtKB/Swiss-Prot:Q91WK1

Gene LinkOut

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