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Bzw2 basic leucine zipper and W2 domains 2 [ Mus musculus (house mouse) ]

Gene ID: 66912, updated on 23-Jun-2021

Summary

Official Symbol
Bzw2provided by MGI
Official Full Name
basic leucine zipper and W2 domains 2provided by MGI
Primary source
MGI:MGI:1914162
See related
Ensembl:ENSMUSG00000020547
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bdm2; HSPC0; HSPC028; 1110001I24Rik
Expression
Broad expression in CNS E18 (RPKM 47.3), CNS E14 (RPKM 41.6) and 18 other tissues See more
Orthologs
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Genomic context

See Bzw2 in Genome Data Viewer
Location:
12; 12 A3
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (36141834..36206922, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (36091835..36156841, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (36818422..36883412, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene tetraspanin 13 Neighboring gene ubiquitin-conjugating enzyme E2F (putative) pseudogene Neighboring gene ribosomal protein S3A pseudogene Neighboring gene ankyrin repeat and MYND domain containing 2 Neighboring gene non-POU-domain-containing, octamer binding protein pseudogene Neighboring gene leucine rich repeat containing 72 Neighboring gene predicted gene, 40390

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC7203

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
basic leucine zipper and W2 domain-containing protein 2
Names
brain development-related molecule 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025840.3NP_080116.2  basic leucine zipper and W2 domain-containing protein 2

    See identical proteins and their annotated locations for NP_080116.2

    Status: VALIDATED

    Source sequence(s)
    AK160544, BQ032572, BY009345
    Consensus CDS
    CCDS25884.1
    UniProtKB/Swiss-Prot
    Q91VK1
    Related
    ENSMUSP00000020856.5, ENSMUST00000020856.6
    Conserved Domains (1) summary
    cd11560
    Location:218408
    W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    36141834..36206922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006515166.4XP_006515229.1  basic leucine zipper and W2 domain-containing protein 2 isoform X1

    Related
    ENSMUST00000221521.2
    Conserved Domains (1) summary
    cl17013
    Location:218369
    W2; C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon
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