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Mrpl55 mitochondrial ribosomal protein L55 [ Mus musculus (house mouse) ]

Gene ID: 67212, updated on 11-Apr-2024

Summary

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Official Symbol
Mrpl55provided by MGI
Official Full Name
mitochondrial ribosomal protein L55provided by MGI
Primary source
MGI:MGI:1914462
See related
Ensembl:ENSMUSG00000036860 AllianceGenome:MGI:1914462
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
L55mt; MRP-L55; 2810038N09Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL55 (mitochondrial ribosomal protein L55). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 24.1), testis adult (RPKM 23.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 B1.3; 11 37.05 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (59093312..59096964)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (59202486..59206138)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene guanylate kinase 1 Neighboring gene STARR-positive B cell enhancer ABC_E6990 Neighboring gene RIKEN cDNA 2610507I01 gene Neighboring gene STARR-positive B cell enhancer ABC_E5232 Neighboring gene RIKEN cDNA 2310033P09 gene Neighboring gene STARR-positive B cell enhancer ABC_E3955 Neighboring gene ADP-ribosylation factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
  2. In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics. Distler U, et al. Proteomics, 2014 Nov. PMID 25211037
  3. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  4. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846
  5. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein mL55
Names
39S ribosomal protein L55, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001302334.2 → NP_001289263.1  large ribosomal subunit protein mL55 isoform 1

    See identical proteins and their annotated locations for NP_001289263.1

    Status: VALIDATED

    Source sequence(s)
    AK012143, AL645854, AV162288, BE652161, BQ031624, BY228808
    Consensus CDS
    CCDS78955.1
    UniProtKB/Swiss-Prot
    Q9CZ83
    Related
    ENSMUSP00000104412.4, ENSMUST00000108784.4
    Conserved Domains (1) summary
    pfam09776
    Location:17 → 131
    Mitoc_L55; Mitochondrial ribosomal protein L55

  2. NM_001302335.2 → NP_001289264.1  large ribosomal subunit protein mL55 isoform 1

    See identical proteins and their annotated locations for NP_001289264.1

    Status: VALIDATED

    Source sequence(s)
    AK012143, AV162288, BE652161, BQ031624, BY228808, CA325878
    Consensus CDS
    CCDS78955.1
    UniProtKB/Swiss-Prot
    Q9CZ83
    Related
    ENSMUSP00000104415.3, ENSMUST00000108787.9
    Conserved Domains (1) summary
    pfam09776
    Location:17 → 131
    Mitoc_L55; Mitochondrial ribosomal protein L55

  3. NM_001302336.2 → NP_001289265.1  large ribosomal subunit protein mL55 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001289265.1

    Status: VALIDATED

    Source sequence(s)
    AK012143, AK012885, AV162288, BY228808
    Consensus CDS
    CCDS24763.1
    UniProtKB/Swiss-Prot
    Q8R030, Q9CZ83
    Related
    ENSMUSP00000048814.6, ENSMUST00000045697.12
    Conserved Domains (1) summary
    pfam09776
    Location:10 → 124
    Mitoc_L55; Mitochondrial ribosomal protein L55

  4. NM_001362908.1 → NP_001349837.1  large ribosomal subunit protein mL55 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645854
    Consensus CDS
    CCDS78955.1
    Related
    ENSMUSP00000104414.2, ENSMUST00000108786.8
    Conserved Domains (1) summary
    pfam09776
    Location:17 → 131
    Mitoc_L55; Mitochondrial ribosomal protein L55

  5. NM_001362909.1 → NP_001349838.1  large ribosomal subunit protein mL55 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL645854
    Consensus CDS
    CCDS24763.1
    UniProtKB/Swiss-Prot
    Q8R030, Q9CZ83
    Conserved Domains (1) summary
    pfam09776
    Location:10 → 124
    Mitoc_L55; Mitochondrial ribosomal protein L55

  6. NM_026035.4 → NP_080311.1  large ribosomal subunit protein mL55 isoform 2 precursor

    See identical proteins and their annotated locations for NP_080311.1

    Status: VALIDATED

    Source sequence(s)
    AK012143, AK012885, AV162288, BB068394, BY228808
    Consensus CDS
    CCDS24763.1
    UniProtKB/Swiss-Prot
    Q8R030, Q9CZ83
    Related
    ENSMUSP00000104413.2, ENSMUST00000108785.2
    Conserved Domains (1) summary
    pfam09776
    Location:10 → 124
    Mitoc_L55; Mitochondrial ribosomal protein L55

RNA

  1. NR_126101.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AA061936, AK012143, AV162288, BY228808

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    59093312..59096964
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030246239.2 → XP_030102099.1  large ribosomal subunit protein mL55 isoform X2

    UniProtKB/Swiss-Prot
    Q8R030, Q9CZ83
    Conserved Domains (1) summary
    pfam09776
    Location:10 → 124
    Mitoc_L55; Mitochondrial ribosomal protein L55

  2. XM_030246240.2 → XP_030102100.1  large ribosomal subunit protein mL55 isoform X2

    UniProtKB/Swiss-Prot
    Q8R030, Q9CZ83
    Conserved Domains (1) summary
    pfam09776
    Location:10 → 124
    Mitoc_L55; Mitochondrial ribosomal protein L55

  3. XM_006533976.4 → XP_006534039.1  large ribosomal subunit protein mL55 isoform X1

    See identical proteins and their annotated locations for XP_006534039.1

    UniProtKB/Swiss-Prot
    Q9CZ83
    Conserved Domains (1) summary
    pfam09776
    Location:17 → 131
    Mitoc_L55; Mitochondrial ribosomal protein L55

  4. XM_030246241.1 → XP_030102101.1  large ribosomal subunit protein mL55 isoform X2

    UniProtKB/Swiss-Prot
    Q8R030, Q9CZ83
    Conserved Domains (1) summary
    pfam09776
    Location:10 → 124
    Mitoc_L55; Mitochondrial ribosomal protein L55

  5. XM_006533975.5 → XP_006534038.1  large ribosomal subunit protein mL55 isoform X1

    See identical proteins and their annotated locations for XP_006534038.1

    UniProtKB/Swiss-Prot
    Q9CZ83
    Conserved Domains (1) summary
    pfam09776
    Location:17 → 131
    Mitoc_L55; Mitochondrial ribosomal protein L55
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CZ83.1 GenPept UniProtKB/Swiss-Prot:Q9CZ83

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