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H2ap H2A.P histone [ Mus musculus (house mouse) ]

Gene ID: 67334, updated on 30-Apr-2024

Summary

Official Symbol
H2approvided by MGI
Official Full Name
H2A.P histoneprovided by MGI
Primary source
MGI:MGI:1914584
See related
Ensembl:ENSMUSG00000040456 AllianceGenome:MGI:1914584
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hypm; H2al3; 1700054O13Rik
Summary
Predicted to enable DNA binding activity. Predicted to be involved in heterochromatin assembly. Predicted to be part of nucleosome. Orthologous to human H2AP (H2A.P histone). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
X A1.1; X 4.61 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (9713186..9713739)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (9846947..9847500)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene H2A histone family member L1O Neighboring gene STARR-seq mESC enhancer starr_46712 Neighboring gene STARR-seq mESC enhancer starr_46713 Neighboring gene dynein light chain Tctex-type 3 Neighboring gene synaptotagmin-like 5 Neighboring gene STARR-seq mESC enhancer starr_46715 Neighboring gene H2A histone family member L3 Neighboring gene STARR-seq mESC enhancer starr_46716 Neighboring gene predicted gene 5754

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleosomal DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of nucleosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
huntingtin-interacting protein M
Names
histone H2A.P
huntingtin interacting protein M
huntingtin yeast partner M

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026096.1NP_080372.1  huntingtin-interacting protein M

    See identical proteins and their annotated locations for NP_080372.1

    Status: VALIDATED

    Source sequence(s)
    AK006788
    Consensus CDS
    CCDS30012.1
    UniProtKB/Swiss-Prot
    Q9CR04
    Related
    ENSMUSP00000043734.2, ENSMUST00000044987.3
    Conserved Domains (1) summary
    smart00414
    Location:2182
    H2A; Histone 2A

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    9713186..9713739
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)