U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp788 zinc finger protein 788 [ Mus musculus (house mouse) ]

Gene ID: 67607, updated on 8-Feb-2024

Summary

Go to the top of the page Help
Official Symbol
Zfp788provided by MGI
Official Full Name
zinc finger protein 788provided by MGI
Primary source
MGI:MGI:1914857
See related
Ensembl:ENSMUSG00000074165 AllianceGenome:MGI:1914857
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810426N06Rik
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 4.9), CNS E14 (RPKM 4.3) and 17 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
7 B3; 7 28.25 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (41282955..41300305)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (41633531..41650881)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 6871 Neighboring gene STARR-seq mESC enhancer starr_18730 Neighboring gene STARR-seq mESC enhancer starr_18731 Neighboring gene STARR-seq mESC enhancer starr_18732 Neighboring gene STARR-positive B cell enhancer ABC_E3716 Neighboring gene predicted gene, 51480 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:48888363-48888572 Neighboring gene vomeronasal 2, receptor, pseudogene 54 Neighboring gene 3-phosphoglycerate dehydrogenase pseudogene Neighboring gene CTD nuclear envelope phosphatase 1 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. Agata Y, et al. Gene, 1998 Jun 15. PMID 9630514
  2. Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry. Hassel S, et al. Proteomics, 2004 May. PMID 15188402
  3. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  5. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein 788

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360674.1 → NP_001347603.1  zinc finger protein 788 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AC108827
    Consensus CDS
    CCDS90214.1
    UniProtKB/TrEMBL
    E9Q980
    Conserved Domains (4) summary
    COG5048
    Location:488 → 883
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:436 → 456
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:23 → 64
    KRAB; KRAB box
    pfam13465
    Location:308 → 332
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001360675.1 → NP_001347604.1  zinc finger protein 788 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AC108827
    Consensus CDS
    CCDS90214.1
    UniProtKB/TrEMBL
    E9Q980
    Related
    ENSMUSP00000096108.3, ENSMUST00000098508.9
    Conserved Domains (4) summary
    COG5048
    Location:488 → 883
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:436 → 456
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:23 → 64
    KRAB; KRAB box
    pfam13465
    Location:308 → 332
    zf-H2C2_2; Zinc-finger double domain

  3. NM_001360677.1 → NP_001347606.1  zinc finger protein 788 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a.
    Source sequence(s)
    AI605193, AK020228, AK163311, CD544822
    Conserved Domains (4) summary
    COG5048
    Location:473 → 868
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:281 → 301
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:8 → 49
    KRAB; KRAB box
    pfam13465
    Location:293 → 317
    zf-H2C2_2; Zinc-finger double domain

  4. NM_001360678.1 → NP_001347607.1  zinc finger protein 788 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct N-terminus compared to isoform a.
    Source sequence(s)
    AC108827
    Consensus CDS
    CCDS90213.1
    UniProtKB/TrEMBL
    E9PZ68
    Related
    ENSMUSP00000035499.8, ENSMUST00000045720.14
    Conserved Domains (4) summary
    COG5048
    Location:468 → 863
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:416 → 436
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:3 → 44
    KRAB; KRAB box
    pfam13465
    Location:288 → 312
    zf-H2C2_2; Zinc-finger double domain

  5. NM_001360680.1 → NP_001347609.1  zinc finger protein 788 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) uses an alternate splice junction compared to variant 1. The resulting isoform (d) is shorter at the N-terminus compared to isoform a. Variants 5-9 all encode the same isoform (d).
    Source sequence(s)
    AC108827
    Consensus CDS
    CCDS39922.1
    UniProtKB/TrEMBL
    Q6PIW5, Q8BUQ3
    Conserved Domains (3) summary
    COG5048
    Location:436 → 831
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:256 → 280
    zf-H2C2_2; Zinc-finger double domain

  6. NM_001360681.1 → NP_001347610.1  zinc finger protein 788 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks an alternate exon and uses an alternate splice junction compared to variant 1. The resulting isoform (d) is shorter at the N-terminus compared to isoform a. Variants 5-9 all encode the same isoform (d).
    Source sequence(s)
    AC108827
    Consensus CDS
    CCDS39922.1
    UniProtKB/TrEMBL
    Q6PIW5, Q8BUQ3
    Related
    ENSMUSP00000132848.2, ENSMUST00000170770.2
    Conserved Domains (3) summary
    COG5048
    Location:436 → 831
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:256 → 280
    zf-H2C2_2; Zinc-finger double domain

  7. NM_001360683.1 → NP_001347612.1  zinc finger protein 788 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and uses an alternate splice junction compared to variant 1. The resulting isoform (d) is shorter at the N-terminus compared to isoform a. Variants 5-9 all encode the same isoform (d).
    Source sequence(s)
    AI605193, AK020228, AK163311, CD544822
    Consensus CDS
    CCDS39922.1
    UniProtKB/TrEMBL
    Q6PIW5, Q8BUQ3
    Conserved Domains (3) summary
    COG5048
    Location:436 → 831
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:256 → 280
    zf-H2C2_2; Zinc-finger double domain

  8. NM_001360684.1 → NP_001347613.1  zinc finger protein 788 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR and uses an alternate splice junction compared to variant 1. The resulting isoform (d) is shorter at the N-terminus compared to isoform a. Variants 5-9 all encode the same isoform (d).
    Source sequence(s)
    AC108827
    Consensus CDS
    CCDS39922.1
    UniProtKB/TrEMBL
    Q6PIW5, Q8BUQ3
    Conserved Domains (3) summary
    COG5048
    Location:436 → 831
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:256 → 280
    zf-H2C2_2; Zinc-finger double domain

  9. NM_023363.3 → NP_075852.1  zinc finger protein 788 isoform d

    See identical proteins and their annotated locations for NP_075852.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and uses an alternate splice junction compared to variant 1. The resulting isoform (d) is shorter at the N-terminus compared to isoform a. Variants 5-9 all encode the same isoform (d).
    Source sequence(s)
    AC108827, AI605193, AK082981
    Consensus CDS
    CCDS39922.1
    UniProtKB/TrEMBL
    Q6PIW5, Q8BUQ3
    Related
    ENSMUSP00000097847.4, ENSMUST00000100275.10
    Conserved Domains (3) summary
    COG5048
    Location:436 → 831
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:256 → 280
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    41282955..41300305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous