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Rnf125 ring finger protein 125 [ Mus musculus (house mouse) ]

Gene ID: 67664, updated on 23-Jun-2021

Summary

Official Symbol
Rnf125provided by MGI
Official Full Name
ring finger protein 125provided by MGI
Primary source
MGI:MGI:1914914
See related
Ensembl:ENSMUSG00000033107
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C730049O14; 4930553F04Rik; C730049O14Rik
Expression
Broad expression in liver adult (RPKM 19.3), testis adult (RPKM 9.0) and 18 other tissues See more
Orthologs
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Genomic context

See Rnf125 in Genome Data Viewer
Location:
18; 18 A2
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (21077672..21120416)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (20944615..20987359)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (21103126..21142349)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 Neighboring gene predicted gene, 31437 Neighboring gene trafficking protein particle complex 8 Neighboring gene ring finger protein 138 Neighboring gene ribosomal protein L27A pseudogene Neighboring gene meprin 1 beta

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables p53 binding ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin conjugating enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ubiquitin protein ligase activity ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin-protein transferase activity EXP
Inferred from Experiment
more info
PubMed 
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
 
part_of VCP-NPL4-UFD1 AAA ATPase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of VCP-NPL4-UFD1 AAA ATPase complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
E3 ubiquitin-protein ligase RNF125
NP_001351902.1
NP_080577.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001364973.1NP_001351902.1  E3 ubiquitin-protein ligase RNF125 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC138611, AK016103, AK050462, BF148133, BY099954
    Consensus CDS
    CCDS89199.1
    Related
    ENSMUSP00000157304.2, ENSMUST00000234316.2
    Conserved Domains (2) summary
    pfam05605
    Location:142174
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    cl17238
    Location:3577
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
  2. NM_026301.3NP_080577.1  E3 ubiquitin-protein ligase RNF125 isoform 1

    See identical proteins and their annotated locations for NP_080577.1

    Status: VALIDATED

    Source sequence(s)
    AC138611, AK050395, AK050462, BF148133
    Consensus CDS
    CCDS29088.1
    UniProtKB/Swiss-Prot
    Q9D9R0
    Related
    ENSMUSP00000058251.2, ENSMUST00000050004.3
    Conserved Domains (1) summary
    pfam05605
    Location:4981
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    21077672..21120416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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