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Scd3 stearoyl-coenzyme A desaturase 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 681458, updated on 3-Apr-2024

Summary

Official Symbol
Scd3provided by RGD
Official Full Name
stearoyl-coenzyme A desaturase 3provided by RGD
Primary source
RGD:1595370
See related
Ensembl:ENSRNOG00000013279 AllianceGenome:RGD:1595370
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable iron ion binding activity; palmitoyl-CoA 9-desaturase activity; and stearoyl-CoA 9-desaturase activity. Predicted to be involved in monounsaturated fatty acid biosynthetic process; response to fatty acid; and unsaturated fatty acid biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human SCD (stearoyl-CoA desaturase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 919.1), Liver (RPKM 799.8) and 8 other tissues See more
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Genomic context

Location:
1q54
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (253028053..253063662)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (243093057..243114451)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (263968156..264003991)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene biogenesis of lysosomal organelles complex-1, subunit 2 Neighboring gene polycystin 2 like 1, transient receptor potential cation channel Neighboring gene RNA, U6 small nuclear 630 Neighboring gene uncharacterized LOC134485240 Neighboring gene uncharacterized LOC134485241 Neighboring gene stearoyl-CoA desaturase, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables iron ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables palmitoyl-CoA 9-desaturase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables palmitoyl-CoA 9-desaturase activity ISO
Inferred from Sequence Orthology
more info
 
enables stearoyl-CoA 9-desaturase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
NOT enables stearoyl-CoA 9-desaturase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in monounsaturated fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within monounsaturated fatty acid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in response to fatty acid IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in unsaturated fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    253028053..253063662
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008760487.4XP_008758709.4  acyl-CoA desaturase 3

    UniProtKB/TrEMBL
    Z4YNJ9