Stpg4 sperm-tail PG-rich repeat containing 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Stpg4provided by RGD
Official Full Name: sperm-tail PG-rich repeat containing 4provided by RGD
Primary source: RGD:1591638
See related: Ensembl:ENSRNOG00000040136 AllianceGenome:RGD:1591638
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in DNA demethylation of male pronucleus and positive regulation of DNA demethylation. Predicted to act upstream of or within C-5 methylation of cytosine. Predicted to be located in cytoplasm and nucleus. Predicted to be active in female pronucleus; germinal vesicle; and male pronucleus. Orthologous to human STPG4 (sperm-tail PG-rich repeat containing 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 169.5) and Adrenal (RPKM 20.0) See more
Orthologs: human mouse all
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Genomic context

Location:: 6q12

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (12860749..12912206)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (7108827..7158519)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (11014596..11063509, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables chromatin binding	ISO Inferred from Sequence Orthology more info
enables histone binding	IBA Inferred from Biological aspect of Ancestor more info
enables histone binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within 5-methylcytosine catabolic process	ISO Inferred from Sequence Orthology more info
involved_in epigenetic programing of male pronucleus	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_positive_effect epigenetic programing of male pronucleus	ISO Inferred from Sequence Orthology more info
involved_in epigenetic programing of male pronucleus	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of DNA demethylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in female germ cell nucleus	ISO Inferred from Sequence Orthology more info
is_active_in female pronucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in female pronucleus	ISO Inferred from Sequence Orthology more info
is_active_in germinal vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in germinal vesicle	ISO Inferred from Sequence Orthology more info
located_in male germ cell nucleus	ISO Inferred from Sequence Orthology more info
is_active_in male pronucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in male pronucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protein STPG4

Names: uncharacterized protein C2orf61 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.