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Rnaset2b ribonuclease T2B [ Mus musculus (house mouse) ]

Gene ID: 68195, updated on 23-Jun-2021

Summary

Official Symbol
Rnaset2bprovided by MGI
Official Full Name
ribonuclease T2Bprovided by MGI
Primary source
MGI:MGI:3702087
See related
Ensembl:ENSMUSG00000094724
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C79750; Rnaset2; RNASE6PL; 0610007O07Rik; 4833423A10Rik; 4930532K22Rik
Expression
Ubiquitous expression in kidney adult (RPKM 173.7), adrenal adult (RPKM 137.4) and 28 other tissues See more
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Genomic context

See Rnaset2b in Genome Data Viewer
Location:
17; 17 A1
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (7246259..7265592)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (6978860..6998193)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (7183209..7202542)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene radial spoke 3B homolog (Chlamydomonas) Neighboring gene T cell activation GTPase activating protein 1 Neighboring gene predicted gene 1604b Neighboring gene predicted gene, 25119 Neighboring gene ribosomal protein S6 kinase, polypeptide 2 Neighboring gene VISTA enhancer mm108

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

General gene information

Markers

Homology

  • Homologs of the Rnaset2b gene: The Rnaset2b gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, A.thaliana, rice, and frog.
  • Orthologs

Clone Names

  • MGC107248

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables endoribonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ribonuclease activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in RNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in RNA catabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum lumen ISO
Inferred from Sequence Orthology
more info
 
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ribonuclease T2-B
Names
ribonuclease 6-B
ribonuclease T2
NP_080887.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026611.2NP_080887.1  ribonuclease T2-B precursor

    See identical proteins and their annotated locations for NP_080887.1

    Status: VALIDATED

    Source sequence(s)
    BC100330, BY004495, CD741736
    Consensus CDS
    CCDS37429.1
    UniProtKB/Swiss-Prot
    C0HKG5, C0HKG6
    UniProtKB/TrEMBL
    Q5FWA0
    Related
    ENSMUSP00000086519.6, ENSMUST00000089119.13
    Conserved Domains (1) summary
    cd01061
    Location:39221
    RNase_T2_euk; Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases). Plant T2 RNases are expressed during leaf ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    7246259..7265592
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_029204.1: Suppressed sequence

    Description
    NM_029204.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript or the encoded protein.
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