Hs3st6 heparan sulfate-glucosamine 3-sulfotransferase 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Hs3st6provided by RGD
Official Full Name: heparan sulfate-glucosamine 3-sulfotransferase 6provided by RGD
Primary source: RGD:1584381
See related: Ensembl:ENSRNOG00000014672 AllianceGenome:RGD:1584381
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Predicted to act upstream of or within blastocyst hatching. Predicted to be located in Golgi apparatus. Orthologous to human HS3ST6 (heparan sulfate-glucosamine 3-sulfotransferase 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 18.9), Lung (RPKM 13.5) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q12

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (14286555..14292660)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (13781999..13788133)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (14122856..14128984)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	IBA Inferred from Biological aspect of Ancestor more info
enables [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within blastocyst hatching	ISO Inferred from Sequence Orthology more info
involved_in heparan sulfate proteoglycan biosynthetic process	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: heparan sulfate glucosamine 3-O-sulfotransferase 6

Names: heparan sulfate (glucosamine) 3-O-sulfotransferase 6

NP_001102920.1

EC 2.8.2.23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109450.1 → NP_001102920.1 heparan sulfate glucosamine 3-O-sulfotransferase 6

See identical proteins and their annotated locations for NP_001102920.1

Status: PROVISIONAL

Source sequence(s)

CH473948

UniProtKB/TrEMBL

A6HCX4, D3ZGJ6

Conserved Domains (1) summary

pfam00685
Location:91 → 326

Sulfotransfer_1; Sulfotransferase domain